ArticleJournal of feline medicine and surgery2004
PCR studies of feline leprosy cases.
Article in Journal of feline medicine and surgery, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Clinical and Pathological Findings Associated with Mycobacteriosis in Captive Syngnathids.Animals : an open access journal from MDPI · 2022Article
- Idiopathic sterile pyogranuloma in three domestic cats.The Journal of small animal practice · 2020Article
- Skin as a marker of general feline health: Cutaneous manifestations of infectious disease.Journal of feline medicine and surgery · 2017Review
- Feline leprosy due to Candidatus 'Mycobacterium lepraefelis': Further clinical and molecular characterisation of eight previously reported cases and an additional 30 cases.Journal of feline medicine and surgery · 2017Observational
- Leprosy - we've much left to learn, but are looking to squirrels, cows and cats for insights.Journal of feline medicine and surgery · 2017Article
- Feline leprosy due to Mycobacterium lepraemurium.Journal of feline medicine and surgery · 2017Article
- History and mysteries of leprosy.Journal of feline medicine and surgery · 2017Article
- Feline leprosy due to Candidatus 'Mycobacterium tarwinense':Further clinical and molecular characterisation of 15 previously reported cases and an additional 27 casesJournal of feline medicine and surgery · 2017Article
- Diffuse Lepromatous Leprosy Due to Mycobacterium lepromatosis in Quintana Roo, Mexico.Journal of clinical microbiology · 2015Article
- Concurrent infection with Cryptococcus neoformans/gattii species complex and Mycobacterium avium affecting the subcutis and bone of a pelvic limb in a cat.Journal of feline medicine and surgery · 2011Article
- Molecular characterization of a novel fastidious mycobacterium causing lepromatous lesions of the skin, subcutis, cornea, and conjunctiva of cats living in Victoria, Australia.Journal of clinical microbiology · 2008Article
- Mycobacterium avium in the postgenomic era.Clinical microbiology reviews · 2007Review
- Disseminated Mycobacterium avium infection in young cats: overrepresentation of Abyssinian cats.Journal of feline medicine and surgery · 2006Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
16S rRNA gene sequence analysis provided evidence for two different mycobacterial species, Mycobacterium lepraemurium and a potentially novel species, as causative agents of 'feline leprosy'. Comparison of 16S rRNA gene sequence data obtained for M. lepraemurium and the potentially novel species indicated 12 nucleotide differences over a 446 bp region encompassing the V2 and V3 hypervariable regions. From available 16S rRNA gene sequence data, M. lepraemurium shared greatest nucleotide identity with M. avium subsp paratuberculosis and M. avium. The novel species had a long helix 18 in the V3 region and shared greatest nucleotide identity with M. leprae, M. haemophilum and M. malmoense. The novel species had an additional 'A' nucleotide at position 105 of the aligned 16S rRNA gene sequence, the only other mycobacterial database sequence having this same extra nucleotide being M. leprae. This nucleotide variation was exploited to develop specific PCR assays for the two species. These were found to be effective and specific when tested against a panel of mycobacteria including species found in feline leprosy lesions and closely related mycobacteria and also when applied directly to formalin-fixed, paraffin-embedded tissues from feline leprosy cases.
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Registered trials
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