Evidence map›Paper›PMID 15262954›Full record

ArticleJournal of bacteriology2004

Expression of a functional secreted YopN-TyeA hybrid protein in Yersinia pestis is the result of a +1 translational frameshift event.

Franco Ferracci, James B Day, Heather J Ezelle, Gregory V Plano

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Regulation of the Yersinia type III secretion system: traffic control.Frontiers in cellular and infection microbiology · 2013
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Timing is everything: the regulation of type III secretion.Cellular and molecular life sciences : CMLS · 2010
    Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Franco FerracciDepartment of Microbiology and Immunology, University of Miami School of Medicine, Miami, FL 33101, USA.
James B Day
Heather J Ezelle
Gregory V Plano
University of Miami · US

Funding

Control of virulence protein export in Yersinia pestisR01AI039575 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PLANO, GREGORY V · 2001 to 2011
$3.3M
Structure of the Yersinia pestis type III export complexR01AI050552 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PLANO, GREGORY V · 2001 to 2004
$903k
CONTROL OF VIRULENCE PROTEIN EXPORT IN YERSINIA PESTISR29AI039575 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PLANO, GREGORY V · 1996 to 2000
$112k
NIAID NIH HHS AI 39575NIAID NIH HHS AI 50552NIAID NIH HHS R01 AI039575NIAID NIH HHS R01 AI050552NIAID NIH HHS R29 AI039575
6 · The paper itself

Abstract

YopN is a secreted protein that prior to secretion directly interacts with the cytosolic SycN/YscB chaperone complex and TyeA. This study identifies a secreted YopN-TyeA hybrid protein that is expressed by Yersinia pestis, but not by Yersinia enterocolitica. DNA sequence analysis and site-directed mutagenesis studies demonstrate that the hybrid protein is the result of a +1 translational frameshift event.

Indexed as

Frameshifting, RibosomalAmino Acid SequenceBacterial Outer Membrane ProteinsBacterial ProteinsBase SequenceCarrier ProteinsIntracellular Signaling Peptides and ProteinsMembrane ProteinsMolecular Sequence DataRecombinant ProteinsYersinia pestisBacterial Outer Membrane ProteinsBacterial ProteinsCarrier ProteinsIntracellular Signaling Peptides and ProteinsMembrane ProteinsRecombinant ProteinsTyeA protein, YersiniaYopN protein, Yersinia

Identifiers

PMID15262954
PMCPMC451632
OpenAlexW2157462470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.