ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2004
Decrease in antibiotic use among children in the 1990s: not all antibiotics, not all children.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Training family physicians in shared decision making for the use of antibiotics for acute respiratory infections: a pilot clustered randomized controlled trial.Health expectations : an international journal of public participation in health care and health policy · 2011Trial
- Does training family physicians in shared decision making promote optimal use of antibiotics for acute respiratory infections? Study protocol of a pilot clustered randomised controlled trial.BMC family practice · 2007Trial
- Association between Broad-Spectrum Antibiotic Use and Risk of Early-Onset Colorectal Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Infant antibiotic exposure and the development of childhood overweight and central adiposity.International journal of obesity (2005) · 2014Article
- Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Determination of antibiotics consumption in buali-sina pediatric hospital, sari 2010-2011.Iranian journal of pharmaceutical research : IJPR · 2014Article
- Systemic antibiotic use among children and adolescents in Germany: a population-based study.European journal of pediatrics · 2013Article
- Impact of delay in asthma diagnosis on chest X-ray and antibiotic utilization by clinicians.The Journal of asthma : official journal of the Association for the Care of Asthma · 2012Article
- Update on acute otitis media in children younger than 2 years of age.Canadian family physician Medecin de famille canadien · 2011Article
- Antibiotic consumption in children prior to diagnosis of asthma.BMC pulmonary medicine · 2011Article
- Effect of regulatory warnings on antidepressant prescription rates, use of health services and outcomes among children, adolescents and young adults.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2008Article
- Antibiotic prescription and prevalence rate in the outpatient paediatric population: analysis of surveys published during 2000-2005.European journal of clinical pharmacology · 2007Review
- Antibiotic availability and the prevalence of pediatric pneumonia during a physicians' strike.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2007Article
- Antibiotic choices by paediatric residents and recently graduated paediatricians for typical infectious disease problems in children.Paediatrics & child health · 2006Article
- Trends in antibiotic utilization in Vancouver associated with a community education program on antibiotic use.Canadian journal of public health = Revue canadienne de sante publiqueArticle
- Evaluation of the prescription and use of antibiotics in Brazilian children.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDecreases in antibiotic use were widely reported in the 1990s. This study was undertaken to determine trends in the use of antibiotics from fiscal year (FY) 1995 (April 1995 to March 1996) to FY 2001 in a complete population of Manitoba children.
methodsUsing Manitoba's health care databases, we determined annual population-based rates of antibiotic prescription among children by antibiotic class (narrow-spectrum and broader-spectrum antibiotics), age group, physician diagnosis (e.g., otitis media or bronchitis) and neighbourhood income in urban areas (derived from the 1996 census). Antibiotic prescription rates were generated within a generalized linear model framework with general estimating equations, and differences between FY 2001 and FY 1995 were tested. Differences in antibiotic use over time were compared across antibiotic classes, age groups, diagnoses and income neighbourhoods.
resultsThe overall antibiotic prescription rate decreased by almost one-third, from 1.2 prescriptions per child in FY 1995 to 0.9 prescriptions in FY 2001. Total antibiotic use declined for all respiratory tract infections; decreases were greatest for the sulfonamides (decrease to less than one-third the FY 1995 rate) and narrow-spectrum macrolides (decrease to less than half the FY 1995 rate). In contrast, the FY 2001 rate for broader-spectrum macrolides was as much as 12.5 times the FY 1995 rate. Otitis media accounted for one-quarter of the use of the latter agents. Preschool children and low-income children received the greatest number of antibiotic prescriptions. Declines in antibiotic prescriptions were of a lesser magnitude for low-income children (for whom rates in FY 2001 were four-fifths the rates in FY 1995) than for higher-income children (for whom rates in FY 2001 were about two-thirds the rates in FY 1995).
interpretationOverall, antibiotic use declined over the late 1990s in this population of Canadian children, but the increasing use of broader-spectrum macrolides and higher rates of antibiotic use among preschool and low-income children may have implications for antibiotic resistance.
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