Evidence map›Paper›PMID 15260939›Full record

ReviewCurrent psychiatry reports2004

Genetics of anxiety disorders.

Paul D Arnold, Gwyneth Zai, Margaret A Richter

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Dorsal raphe nucleus and harm avoidance: A resting-state investigation.Cognitive, affective & behavioral neuroscience · 2016
    Article
  5. Article
  6. Article
  7. Family accommodation in obsessive-compulsive disorder.Expert review of neurotherapeutics · 2012
    Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paul D ArnoldAnxiety Disorders Clinic, Centre for Addiction and Mental Health, University of Toronto, 250 College Street, Toronto, ON M5T 1R8, Canada.
Gwyneth Zai
Margaret A Richter

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is considerable evidence that genetic determinants play a major role in the etiology of anxiety. Investigations into susceptibility genes for anxiety are well underway, particularly for panic disorder and obsessive-compulsive disorder and more broadly defined anxiety-related traits, such as neuroticism and harm avoidance. This review will discuss some of the core issues related to diagnosis and molecular genetic methodology, followed by a review of recent molecular genetic findings for anxiety. The authors will attempt to highlight the numerous convergent and exciting findings. Given the rapid acceleration in knowledge of the human genome, a more definitive understanding of the genetic roots of these complex conditions may be anticipated in the relatively near future.

Indexed as

Anxiety DisordersBrain-Derived Neurotrophic FactorCatechol O-MethyltransferaseChildCholecystokininGene ExpressionGenetic LinkageGlutamic AcidHumansInhibition, PsychologicalMembrane GlycoproteinsMembrane Transport ProteinsMolecular BiologyNerve Tissue ProteinsNeurotic DisordersObsessive-Compulsive DisorderBrain-Derived Neurotrophic FactorCatechol O-MethyltransferaseCholecystokininGlutamic AcidMembrane GlycoproteinsMembrane Transport ProteinsNerve Tissue ProteinsSerotoninSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, human

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.