ReviewFolia microbiologica2004
Tick saliva in anti-tick immunity and pathogen transmission.
Review in Folia microbiologica, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Arthropod exosomal glycine-rich protein as a potential vaccine candidate effectively reduces tick blood-feeding and pathogen transmission.The EMBO journal · 2026Article
- Acquired tick resistance inInfection and immunity · 2025Article
- Tick saliva and its role in pathogen transmission.Wiener klinische Wochenschrift · 2023Article
- Article
- How ticks keep ticking in the adversity of host immune reactions.Journal of mathematical biology · 2019Article
- An Immunosuppressive Tick Salivary Gland Protein DsCystatin Interferes With Toll-Like Receptor Signaling by Downregulating TRAF6.Frontiers in immunology · 2018Article
- Interaction between saliva's adenosine and tick parasitism: effects on feeding and reproduction.Parasites & vectors · 2017Article
- Salivary Tick Cystatin OmC2 Targets Lysosomal Cathepsins S and C in Human Dendritic Cells.Frontiers in cellular and infection microbiology · 2017Article
- Target validation of highly conserved Amblyomma americanum tick saliva serine protease inhibitor 19.Ticks and tick-borne diseases · 2016Article
- Seasonal variation in infestations by ixodids on Siberian chipmunks: effects of host age, sex, and birth season.Parasitology research · 2015Article
- Amblyomma americanum tick calreticulin binds C1q but does not inhibit activation of the classical complement cascade.Ticks and tick-borne diseases · 2015Article
- Understanding the evolutionary structural variability and target specificity of tick salivary Kunitz peptides using next generation transcriptome data.BMC evolutionary biology · 2014Article
- A deep insight into the sialotranscriptome of the gulf coast tick, Amblyomma maculatum.PloS one · 2011Article
- Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks.The Journal of clinical investigation · 2010Article
- Variations in Ixodes ricinus density and Borrelia infections associated with cattle introduced into a woodland in The Netherlands.Applied and environmental microbiology · 2008Article
- Variability and action mechanism of a family of anticomplement proteins in Ixodes ricinus.PloS one · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When feeding on vertebrate host ticks (ectoparasitic arthropods and potential vectors of bacterial, rickettsial, protozoal, and viral diseases) induce both innate and specific acquired host-immune reactions as part of anti-tick defenses. In a resistant host immune defense can lead to reduced tick viability, sometimes resulting in tick death. Tick responds to the host immune attack by secreting saliva containing pharmacologically active molecules and modulating host immune response. Tick saliva-effected immunomodulation at the attachment site facilitates both tick feeding and enhances the success of transmission of pathogens from tick into the host. On the other hand, host immunization with antigens from tick saliva can induce anti-tick resistance and is seen to be able to induce immunity against pathogens transmitted by ticks. Many pharmacological properties of saliva described in ticks are shared widely among other blood-feeding arthropods.
Indexed as
Identifiers
15259776What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.