ArticleBMC genetics2004
Nucleotide diversity of the ZmPox3 maize peroxidase gene: relationships between a MITE insertion in exon 2 and variation in forage maize digestibility.
Article in BMC genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 80 citations in OpenAlex.
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- Genetic variability of aquaporin expression in maize: From eQTLs to a MITE insertion regulating PIP2;5 expression.Plant physiology · 2024Article
- Breeding for improved digestibility and processing of lignocellulosic biomass inFrontiers in plant science · 2024Review
- High-Throughput Phenotyping Accelerates the Dissection of the Phenotypic Variation and Genetic Architecture of Shank Vascular Bundles in Maize (Plants (Basel, Switzerland) · 2022Article
- Transcriptome dynamic landscape underlying the improvement of maize lodging resistance under coronatine treatment.BMC plant biology · 2021Article
- Genetic mapping and genomic selection for maize stalk strength.BMC plant biology · 2020Article
- Identification of TaPPH-7A haplotypes and development of a molecular marker associated with important agronomic traits in common wheat.BMC plant biology · 2019Article
- Genome-wide association analysis of forage quality in maize mature stalk.BMC plant biology · 2016Article
- Genome-Wide Association Study Reveals the Genetic Basis of Stalk Cell Wall Components in Maize.PloS one · 2016Article
- Maize peroxidase Px5 has a highly conserved sequence in inbreds resistant to mycotoxin producing fungi which enhances fungal and insect resistance.Journal of plant research · 2016Article
- A MITE transposon insertion is associated with differential methylation at the maize flowering time QTL Vgt1.G3 (Bethesda, Md.) · 2014Article
- Comparative nucleotide diversity across North American and European populus species.Journal of molecular evolution · 2012Article
- An analysis of the polymorphisms in a gene for being involved in drought tolerance in maize.Genetica · 2011Article
- Epistatic interactions between Opaque2 transcriptional activator and its target gene CyPPDK1 control kernel trait variation in maize.Plant physiology · 2009Article
- Scanning the genome for gene single nucleotide polymorphisms involved in adaptive population differentiation in white spruce.Molecular ecology · 2008Article
- Characterization of phenylpropanoid pathway genes within European maize (Zea mays L.) inbreds.BMC plant biology · 2008Article
- Application of association mapping to understanding the genetic diversity of plant germplasm resources.International journal of plant genomics · 2008Article
- MAIZEWALL. Database and developmental gene expression profiling of cell wall biosynthesis and assembly in maize.Plant physiology · 2007Article
- High levels of linkage disequilibrium and associations with forage quality at a phenylalanine ammonia-lyase locus in European maize (Zea mays L.) inbreds.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2007Article
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPolymorphisms were investigated within the ZmPox3 maize peroxidase gene, possibly involved in lignin biosynthesis because of its colocalization with a cluster of QTL related to lignin content and cell wall digestibility. The purpose of this study was to identify, on the basis of 37 maize lines chosen for their varying degrees of cell wall digestibility and representative of temperate regions germplasm, ZmPox3 haplotypes or individual polymorphisms possibly associated with digestibility.
resultsNumerous haplotypes with high diversity were identified. Frequency of nucleotide changes was high with on average one SNP every 57 bp. Nucleotide diversity was not equally distributed among site categories: the estimated pi was on average eight times higher for silent sites than for non-synonymous sites. Numerous sites were in linkage disequilibrium that decayed with increasing physical distance. A zmPox3 mutant allele, carrying an insertion of a transposable element in the second exon, was found in lines derived from the early flint inbred line, F7. This element possesses many structural features of miniature inverted-repeat transposable elements (MITE). The mutant allele encodes a truncated protein lacking important functional sites. An ANOVA performed with a subset of 31 maize lines indicated that the transposable element was significantly associated with cell wall digestibility. This association was confirmed using an additional set of 25 flint lines related to F7. Moreover, RT-PCR experiments revealed a decreased amount of corresponding mRNA in plants with the MITE insertion.
conclusionThese results showed that ZmPox3 could possibly be involved in monolignol polymerisation, and that a deficiency in ZmPox3 peroxidase activity seemingly has a negative effect on cell wall digestibility. Also, genetic diversity analyses of ZmPox3 indicated that this peroxidase could be a relevant target for grass digestibility improvement using specific allele introgressions.
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