Evidence map›Paper›PMID 15257377›Full record

ReviewDer Nervenarzt2004

[Multiple sclerosis: potential therapeutic options and update of ongoing studies].

H Wiendl, H C Lehmann, R Hohlfeld, H-P Hartung, B C Kieseier

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Nervenarzt, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H WiendlAbteilung für Allgemeine Neurologie und Hertie-Institut für Klinische Hirnforschung, Neurologische Klinik der Eberhard-Karls-Universität Tübingen. heinz.wiendl@uni-tuebingen.de
H C Lehmann
R Hohlfeld
H-P Hartung
B C Kieseier

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic options for the treatment of multiple sclerosis (MS) have experienced enormous progress over recent years. Despite these encouraging developments, available therapies are only partially effective, and the ultimate goal of curing MS is still far from being attained. The improved understanding of the cellular and molecular mechanisms of MS (immune) pathogenesis together with recent shifts in paradigms led to a variety of new therapeutic targets and approaches. In addition to modulation of the inflammatory process, therapeutic approaches focussing on active neuroprotection, remyelinization, and regeneration have become increasingly important. Based on current concepts of the MS pathogenesis, this article summarizes new therapeutic approaches. Substances and strategies currently tested in clinical trials are reviewed.

Indexed as

Adjuvants, ImmunologicAntibodies, MonoclonalClinical Trials as TopicDisease ProgressionHumansMultiple SclerosisNeuroprotective AgentsPatient Care ManagementPractice Guidelines as TopicTreatment OutcomeAdjuvants, ImmunologicAntibodies, MonoclonalNeuroprotective Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.