Evidence map›Paper›PMID 15256064›Full record

ReviewJournal of cellular and molecular medicine

Intracellular calcium signals and control of cell proliferation: how many mechanisms?

L Munaron, S Antoniotti, D Lovisolo

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Article
  3. iScience · 2025
    Article
  4. Article
  5. Article
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  8. Photobiomodulation in 3D tissue engineering.Journal of biomedical optics · 2022
    Article
  9. Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics.Reviews of physiology, biochemistry and pharmacology · 2022
    Review
  10. Article
  11. Olfactory Receptor OR7A17 Expression Correlates with All-International journal of molecular sciences · 2021
    Article
  12. Review
  13. Article
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  15. Review
  16. Article
  17. Article
  18. Article
  19. Phorbol 12-myristate 13-acetate (PMA) suppresses high CaThe journal of physiological sciences : JPS · 2019
    Article
  20. Anti-Cancer Agents in Proliferation and Cell Death: The Calcium Connection.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

L MunaronDepartment of Animal and Human Biology, University of Torino, Via Accademia Albertina 13, 10123, Torino, Italy. luca.munaron@unito.it
S Antoniotti
D Lovisolo
University of Turin · ITAccademia Albertina delle Belle Arti · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The progression through the cell cycle in non-transformed cells is under the strict control of extracellular signals called mitogens, that act by eliciting complex cascades of intracellular messengers. Among them, increases in cytosolic free calcium concentration have been long realized to play a crucial role; however, the mechanisms coupling membrane receptor activation to calcium signals are still only partially understood, as are the pathways of calcium entry in the cytosol. This article centers on the role of calcium influx from the extracellular medium in the control of proliferative processes, and reviews the current understanding of the pathways responsible for this influx and of the second messengers involved in their activation.

Indexed as

Calcium SignalingCell ProliferationAnimalsCalciumCalcium Channel BlockersCalcium ChannelsHumansCalciumCalcium Channel BlockersCalcium Channels

Identifiers

PMID15256064
PMCPMC6740139
OpenAlexW2070080171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.