ArticleProceedings. Biological sciences2004
Unravelling migrations in the steppe: mitochondrial DNA sequences from ancient central Asians.
Article in Proceedings. Biological sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Ancestral Origins and Admixture History of Kazakhs.Molecular biology and evolution · 2024Article
- Reconstructing complex admixture history using a hierarchical model.Briefings in bioinformatics · 2024Article
- Article
- Mitochondrial DNA Footprints from Western Eurasia in Modern Mongolia.Frontiers in genetics · 2021Article
- Genetic Relationship Among the Kazakh People Based on Y-STR Markers Reveals Evidence of Genetic Variation Among Tribes and Zhuz.Frontiers in genetics · 2021Article
- Type 2 diabetes mellitus: distribution of genetic markers in Kazakh population.Clinical interventions in aging · 2018Article
- Mitogenomic data indicate admixture components of Central-Inner Asian and Srubnaya origin in the conquering Hungarians.PloS one · 2018Article
- Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study.BMC medical genetics · 2017Article
- Diverse origin of mitochondrial lineages in Iron Age Black Sea Scythians.Scientific reports · 2017Article
- Ancestry and demography and descendants of Iron Age nomads of the Eurasian Steppe.Nature communications · 2017Article
- Maternal Genetic Ancestry and Legacy of 10(th) Century AD Hungarians.Scientific reports · 2016Article
- Analysis of ancient human mitochondrial DNA from the Xiaohe cemetery: insights into prehistoric population movements in the Tarim Basin, China.BMC genetics · 2015Article
- Article
- Ancient DNA reveals key stages in the formation of central European mitochondrial genetic diversity.Science (New York, N.Y.) · 2013Article
- Mitochondrial and Y-chromosomal profile of the Kazakh population from East Kazakhstan.Croatian medical journal · 2013Article
- Article
- Tracing the origin of the east-west population admixture in the Altai region (Central Asia).PloS one · 2012Article
- In the heartland of Eurasia: the multilocus genetic landscape of Central Asian populations.European journal of human genetics : EJHG · 2011Article
- Genetic diversity among ancient Nordic populations.PloS one · 2010Article
- The mtDNA composition of Uzbekistan: a microcosm of Central Asian patterns.International journal of legal medicine · 2010Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
This study helps to clarify the debate on the Western and Eastern genetic influences in Central Asia. Thirty-six skeletal remains from Kazakhstan (Central Asia), excavated from different sites dating between the fifteenth century BC to the fifth century AD, have been analysed for the hypervariable control region (HVR-I) and haplogroup diagnostic single nucleotide polymorphisms (SNPs) of the mitochondrial DNA genome. Standard authentication criteria for ancient DNA studies, including multiple extractions, cloning of PCR products and independent replication, have been followed. The distribution of east and west Eurasian lineages through time in the region is concordant with the available archaeological information: prior to the thirteenth-seventh century BC, all Kazakh samples belong to European lineages; while later an arrival of east Eurasian sequences that coexisted with the previous west Eurasian genetic substratum can be detected. The presence of an ancient genetic substratum of European origin in West Asia may be related to the discovery of ancient mummies with European features in Xinjiang and to the existence of an extinct Indo-European language, Tocharian. This study demonstrates the usefulness of the ancient DNA in unravelling complex patterns of past human migrations so as to help decipher the origin of present-day admixed populations.
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