ReviewJournal of bioenergetics and biomembranes2000
Stoichiometry of energy coupling by proton-translocating ATPases: a history of variability.
Review in Journal of bioenergetics and biomembranes, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 69 citations in OpenAlex.
- Expanding the phenotype and metabolic basis of ATP6AP2-congenital disorder of glycosylation in a Chinese patient with a novel variant c.185G>A (p.Gly62Glu).Frontiers in genetics · 2023Article
- Laboratory evolution of synthetic electron transport system variants reveals a larger metabolic respiratory system and its plasticity.Nature communications · 2022Article
- Metabolic energy conservation for fermentative product formation.Microbial biotechnology · 2021Review
- Targeting Mitochondrial Singlet Oxygen Dynamics Offers New Perspectives for Effective Metabolic Therapies of Cancer.Frontiers in oncology · 2020Review
- Ranking network mechanisms by how they fit diverse experiments and deciding onNPJ systems biology and applications · 2019Article
- Energetic evolution of cellular Transportomes.BMC genomics · 2018Article
- Modeling and simulation of the redox regulation of the metabolism inBiotechnology for biofuels · 2017Article
- Article
- Dynamic exometabolome analysis reveals active metabolic pathways in non-replicating mycobacteria.Environmental microbiology · 2015Article
- The genetic basis of energy conservation in the sulfate-reducing bacterium Desulfovibrio alaskensis G20.Frontiers in microbiology · 2014Article
- Comparison of the H+/ATP ratios of the H+-ATP synthases from yeast and from chloroplast.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Influence of stereochemistry on proton transfer in protonated tripeptide models.Journal of molecular modeling · 2012Article
- F1F0-ATP synthases of alkaliphilic bacteria: lessons from their adaptations.Biochimica et biophysica acta · 2010Review
- Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level phosphorylation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2010Article
- Variation in bacterial ATP level and proton motive force due to adhesion to a solid surface.Applied and environmental microbiology · 2009Article
- Constant c10 ring stoichiometry in the Escherichia coli ATP synthase analyzed by cross-linking.Journal of bacteriology · 2009Article
- The thermodynamic H+/ATP ratios of the H+-ATPsynthases from chloroplasts and Escherichia coli.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive force.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Modeling of oxygen transport and cellular energetics explains observations on in vivo cardiac energy metabolism.PLoS computational biology · 2006Article
- A biophysical model of the mitochondrial respiratory system and oxidative phosphorylation.PLoS computational biology · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the central energy-coupling reactions in living systems is the intraconversion of ATP with a transmembrane proton gradient, carried out by proton-translocating F- and V-type ATPases/synthases. These reversible enzymes can hydrolyze ATP and pump protons, or can use the energy of a transmembrane proton gradient to synthesize ATP from ADP and inorganic phosphate. The stoichiometry of these processes (H(+)/ATP, or coupling ratio) has been studied in many systems for many years, with no universally agreed upon solution. Recent discoveries concerning the structure of the ATPases, their assembly and the stoichiometry of their numerous subunits, particularly the proton-carrying proteolipid (subunit c) of the F(O) and V(0) sectors, have shed new light on this question and raise the possibility of variable coupling ratios modulated by variable proteolipid stoichiometries.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.