ArticlePlanta2004
The DNA-binding protease, CND41, and the degradation of ribulose-1,5-bisphosphate carboxylase/oxygenase in senescent leaves of tobacco.
Article in Planta, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 156 citations in OpenAlex.
- Chloroplast Protein Degradation Pathways During Leaf Senescence: Coordination and Roles in Nitrogen Remobilization.Plants (Basel, Switzerland) · 2026Review
- The liquid from carnivorous marsh pitcher plants (Heliamphora sp.) contains endogenous enzymes for prey digestion.Planta · 2026Article
- PtCP1 Is an Extraplastidial Cysteine Protease Involved in Leaf Protein Degradation ofPlants (Basel, Switzerland) · 2026Article
- How the diversity in digestion in carnivorous plants may have evolved.The New phytologist · 2025Review
- Genome-wide identification and expression patterns of the aspartic protease gene family in Epimedium pubescens.BMC genomics · 2025Article
- Validation of stay-green and stem reserve mobilization QTLs: physiological and gene expression approach.Frontiers in plant science · 2025Article
- Characterizing the extractable proteins from tomato leaves - A proteomics study.Food chemistry: X · 2025Article
- Intra-chloroplast proteases: A holistic network view of chloroplast proteolysis.The Plant cell · 2024Review
- Cathepsin B degrades RbcL during freezing-induced programmed cell death in Arabidopsis.Plant cell reports · 2024Article
- Transcriptomic profiling of near-isogenic lines reveals candidate genes for a significant locus conferring metribuzin resistance in wheat.BMC plant biology · 2023Article
- Chloroplast proteostasis: A story of birth, life, and death.Plant communications · 2023Review
- Multivariate analysis and genetic dissection of staygreen and stem reserve mobilisation under combined drought and heat stress in wheat (Frontiers in genetics · 2023Article
- The grapevine aspartic protease gene family: characterization and expression modulation in response to Plasmopara viticola.Journal of plant research · 2022Article
- Molecular basis of nitrogen starvation-induced leaf senescence.Frontiers in plant science · 2022Review
- Chloroplast dismantling in leaf senescence.Journal of experimental botany · 2021Review
- Leaf senescence: progression, regulation, and application.Molecular horticulture · 2021Review
- Low Light/Darkness as Stressors of Multifactor-Induced Senescence in Rice Plants.International journal of molecular sciences · 2021Review
- Genome-wide identification of the aspartic protease gene family and their response under powdery mildew stress in wheat.Molecular biology reports · 2020Article
- Regulation of senescence-associated protease genes by sulphur availability according to barley (Hordeum vulgare L.) phenological stage.Annals of botany · 2020Article
- Molecular Properties and New Potentials of Plant Nepenthesins.Plants (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plastids bear their own genome, organized into DNA-protein complexes (nucleoids). Recently, we identified a DNA-binding protease (CND41) in the chloroplast nucleoids of cultured tobacco (Nicotiana tabacum L.) cells. In this study, we examine the biochemical function of this novel DNA-binding protease, particularly in senescent leaves, because antisense tobacco with a reduced amount of CND41 showed retarded senescence. Nitrogen-depletion experiments clearly showed that CND41 antisense tobacco maintained green leaves and constant protein levels, especially ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), throughout the whole plant, whereas wild-type tobacco showed marked senescence and the reduction of protein levels in the lower leaves. In vitro analyses confirmed that CND41 showed proteolytic activity at physiological pH when denatured Rubisco was used as the substrate. These results suggest that CND41 is involved in Rubisco degradation and the translocation of nitrogen during senescence. The possible regulation of protease activity of CND41 through DNA-binding is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.