Evidence map›Paper›PMID 15249303›Full record

ArticleAmerican journal of public health2004

Vaccination and allergic disease: a birth cohort study.

Tricia M McKeever, Sarah A Lewis, Chris Smith, Richard Hubbard

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of public health, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06286007 (Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control), which is not on this map. Cited by 30 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 5 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06286007 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prevalence and Impact of Pertussis and RSV on Asthma Severity and Control

Typeobservational_patient_registrySponsorHospital Clinico Universitario de SantiagoRan2023 to 2026Enrolled784ConditionsAsthma, Pertussis, RSV InfectionArmsPCR
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 5 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Vaccines for measles, mumps, rubella, and varicella in children.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Vaccines for measles, mumps, rubella, and varicella in children.The Cochrane database of systematic reviews · 2020
    Pooled it
  5. Vaccines for measles, mumps and rubella in children.The Cochrane database of systematic reviews · 2012
    Pooled it
  6. Trial
  7. Article
  8. Article
  9. Artificial intelligence-driven reverse vaccinology forFrontiers in molecular biosciences · 2024
    Article
  10. Article
  11. Insight into the first multi-epitope-based peptide subunit vaccine against avian influenza A virus (H5N6): An immunoinformatics approach.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022
    Article
  12. S3 guideline Allergy Prevention.Allergologie select · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. In silico-based vaccine design against Ebola virus glycoprotein.Advances and applications in bioinformatics and chemistry : AABC · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tricia M McKeeverClinical Science Building, City Hospital, Nottingham NG5 1PB, England, UK. tricia.mckeever@nottingham.ac.uk
Sarah A Lewis
Chris Smith
Richard Hubbard
University of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe examined the effect of vaccination for diphtheria; polio; pertussis and tetanus; or measles, mumps, and rubella on the incidence of physician-diagnosed asthma and eczema.

methodsWe used a previously established birth cohort in the West Midlands General Practice research database.

resultsWe found an association between vaccination and the development of allergic disease; however, this association was present only among children with the fewest physician visits and can be explained by this factor.

conclusionsOur data suggest that currently recommended routine vaccinations are not a risk factor for asthma or eczema.

Indexed as

AsthmaChildChild, PreschoolCohort StudiesEczemaEnglandFemaleHumansInfantInfant, NewbornMalePhysicians, FamilyVaccination

Identifiers

PMID15249303
PMCPMC1448377
OpenAlexW1982817031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.