ArticleInternational journal of legal medicine2004
Mitochondrial DNA control region sequences from Nairobi (Kenya): inferring phylogenetic parameters for the establishment of a forensic database.
Article in International journal of legal medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 119 citations in OpenAlex.
- Forensic biobank; towards comprehensive forensic genetic frequency database for the Kenyan population.Forensic science international. Synergy · 2025Article
- Impact of patrilocality on contrasting patterns of paternal and maternal heritage in Central-West Africa.Scientific reports · 2024Article
- Maternal ancestry and lineages diversity of the Santander population from Colombia.Forensic sciences research · 2023Article
- Comprehensive analysis of mitochondrial and nuclear DNA variations in patients affected by hemoglobinopathies: A pilot study.PloS one · 2020Article
- Mitochondrial DNA control region diversity in a population from Parana state-increasing the Brazilian forensic database.International journal of legal medicine · 2019Article
- Sequence polymorphism data of the hypervariable regions of mitochondrial DNA in the Yadav population of Haryana.Data in brief · 2018Article
- Data on haplotype diversity in the hypervariable region I, II and III of mtDNA amongst the Brahmin population of Haryana.Data in brief · 2018Article
- Article
- Demographic History of Indigenous Populations in Mesoamerica Based on mtDNA Sequence Data.PloS one · 2015Article
- Mitochondrial control region variation in a Korean population sample.International journal of legal medicine · 2014Article
- Article
- Personal identification of cold case remains through combined contribution from anthropological, mtDNA, and bomb-pulse dating analyses.Journal of forensic sciences · 2012Article
- Forensic and phylogeographic characterisation of mtDNA lineages from Somalia.International journal of legal medicine · 2012Article
- MtDNA diversity of Ghana: a forensic and phylogeographic view.Forensic science international. Genetics · 2012Article
- Interdisciplinary approach to the demography of Jamaica.BMC evolutionary biology · 2012Article
- An alternative model for the early peopling of southern South America revealed by analyses of three mitochondrial DNA haplogroups.PloS one · 2012Article
- Evaluating sequence-derived mtDNA length heteroplasmy by amplicon size analysis.Forensic science international. Genetics · 2011Article
- SAM: String-based sequence search algorithm for mitochondrial DNA database queries.Forensic science international. Genetics · 2011Article
- Homogeneity in mitochondrial DNA control region sequences in Swedish subpopulations.International journal of legal medicine · 2010Article
- Investigation of heteroplasmy in the human mitochondrial DNA control region: a synthesis of observations from more than 5000 global population samples.Journal of molecular evolution · 2009Article
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large forensic mtDNA databases which adhere to strict guidelines for generation and maintenance, are not available for many populations outside of the United States and western Europe. We have established a high quality mtDNA control region sequence database for urban Nairobi as both a reference database for forensic investigations, and as a tool to examine the genetic variation of Kenyan sequences in the context of known African variation. The Nairobi sequences exhibited high variation and a low random match probability, indicating utility for forensic testing. Haplogroup identification and frequencies were compared with those reported from other published studies on African, or African-origin populations from Mozambique, Sierra Leone, and the United States, and suggest significant differences in the mtDNA compositions of the various populations. The quality of the sequence data in our study was investigated and supported using phylogenetic measures. Our data demonstrate the diversity and distinctiveness of African populations, and underline the importance of establishing additional forensic mtDNA databases of indigenous African populations.
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