ArticlePlant physiology2004
Contrasting modes of diversification in the Aux/IAA and ARF gene families.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 158 papers.
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Who cites it
158 citing papers in PubMed, 317 citations in OpenAlex.
- Genome-Wide Identification of thePlants (Basel, Switzerland) · 2026Article
- Evolutionary and functional analysis of ARF and Aux/IAA gene families reveals their roles in sugar metabolism and watermelon domestication.Frontiers in plant science · 2026Article
- Genome-Wide Identification and Expression Profiling of theInternational journal of molecular sciences · 2025Article
- Characterisation of theInternational journal of molecular sciences · 2025Article
- Systematic analysis of the Aux/IAA gene family in pineapple reveals insights into their structural diversity, expression dynamics, and interaction networks.BMC plant biology · 2025Article
- Bioinformatics Analysis Reveals the Evolutionary Characteristics of theInternational journal of molecular sciences · 2025Article
- Expression analysis of genes enriched in the pulvinus ofPlant biotechnology (Tokyo, Japan) · 2025Article
- Genome-wide identification and functional analysis of the ARF gene family in tetraploid potato reveal its potential role in anthocyanin biosynthesis.BMC plant biology · 2025Article
- Functional Divergence of the Closely Related Genes PhARF5 and PhARF19a inInternational journal of molecular sciences · 2024Article
- Overexpression of Auxin/Indole-3-Acetic Acid Gene TrIAA27 Enhances Biomass, Drought, and Salt Tolerance inPlants (Basel, Switzerland) · 2024Article
- Genome-Wide Analysis of the Auxin/Indoleacetic Acid (International journal of molecular sciences · 2024Article
- Two auxins are better than one: BiAux joins forces with auxin to enhance lateral root formation.Plant physiology · 2024Article
- Identification of ARF genes in Juglans Sigillata Dode and analysis of their expression patterns under drought stress.Molecular biology reports · 2024Article
- Article
- Genome-Wide Identification and Analysis of the Aux/IAA Gene Family inInternational journal of molecular sciences · 2024Article
- Identification of potential auxin response candidate genes for soybean rapid canopy coverage through comparative evolution and expression analysis.Frontiers in plant science · 2024Article
- Identification of potential Auxin Response Candidate genes for soybean rapid canopy coverage through comparative evolution and expression analysis.bioRxiv : the preprint server for biology · 2023Article
- Dynamic context-dependent regulation of auxin feedback signaling in synthetic gene circuits.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Identification of a novel viral factor inducing tumorous symptoms by disturbing vascular developmentJournal of virology · 2023Article
- Genome-wide investigation of ARF transcription factor gene family and its responses to abiotic stress in Coix (Coix lacryma-jobi L.).Protoplasma · 2023Article
98 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The complete genomic sequence for Arabidopsis provides the opportunity to combine phylogenetic and genomic approaches to study the evolution of gene families in plants. The Aux/IAA and ARF gene families, consisting of 29 and 23 loci in Arabidopsis, respectively, encode proteins that interact to mediate auxin responses and regulate various aspects of plant morphological development. We developed scenarios for the genomic proliferation of the Aux/IAA and ARF families by combining phylogenetic analysis with information on the relationship between each locus and the previously identified duplicated genomic segments in Arabidopsis. This analysis shows that both gene families date back at least to the origin of land plants and that the major Aux/IAA and ARF lineages originated before the monocot-eudicot divergence. We found that the extant Aux/IAA loci arose primarily through segmental duplication events, in sharp contrast to the ARF family and to the general pattern of gene family proliferation in Arabidopsis. Possible explanations for the unusual mode of Aux/IAA duplication include evolutionary constraints imposed by complex interactions among proteins and pathways, or the presence of long-distance cis-regulatory sequences. The antiquity of the two gene families and the unusual mode of Aux/IAA diversification have a number of potential implications for understanding both the functional and evolutionary roles of these genes.
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