ReviewGut2004
Iron, anaemia, and inflammatory bowel diseases.
Review in Gut, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05225545 (Randomized Controlled Trial of Sucrosomial Iron vs. Oral Iron Sulfate for the Treatment of Iron Deficiency Anemia in Patients With Ulcerative Colitis), which is not on this map. Cited by 168 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomized Controlled Trial of Sucrosomial Iron vs. Oral Iron Sulfate for the Treatment of Iron Deficiency Anemia in Patients With Ulcerative Colitis
Who cites it
168 citing papers in PubMed, 10 syntheses or guidelines pooled it, 496 citations in OpenAlex.
- Risk factors of inflammatory bowel disease complicating anemia: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Approach to anaemia in gastrointestinal disease: A position paper by the ESPGHAN Gastroenterology Committee.Journal of pediatric gastroenterology and nutrition · 2025Guideline
- Nutrition, Nutritional Status, Micronutrients Deficiency, and Disease Course of Inflammatory Bowel Disease.Nutrients · 2023Pooled it
- Pooled it
- ACG Clinical Guideline: Management of Crohn's Disease in Adults.The American journal of gastroenterology · 2018Guideline
- Pooled it
- Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review.Medicine · 2015Pooled it
- Ferrous sulfate supplementation causes significant gastrointestinal side-effects in adults: a systematic review and meta-analysis.PloS one · 2015Pooled it
- Treatment of anemia in inflammatory bowel disease--systematic review and meta-analysis.PloS one · 2013Pooled it
- Does Helicobacter pylori infection play a role in iron deficiency anemia? A meta-analysis.World journal of gastroenterology · 2010Pooled it
- Trial
- Effectiveness and safety of ferric carboxymaltose compared to iron sucrose in women with iron deficiency anemia: phase IV clinical trials.BMC women's health · 2018Trial
- Randomized Open-Label Phase 1 Study of the Pharmacokinetics of Ferric Maltol in Inflammatory Bowel Disease Patients with Iron Deficiency.European journal of drug metabolism and pharmacokinetics · 2017Trial
- High-dose fast infusion of parenteral iron isomaltoside is efficacious in inflammatory bowel disease patients with iron-deficiency anaemia without profound changes in phosphate or fibroblast growth factor 23.Scandinavian journal of gastroenterology · 2016Trial
- Serum Hepcidin and Iron Absorption in Paediatric Inflammatory Bowel Disease.Journal of Crohn's & colitis · 2016Trial
- Trial
- Ferric maltol is effective in correcting iron deficiency anemia in patients with inflammatory bowel disease: results from a phase-3 clinical trial program.Inflammatory bowel diseases · 2015Trial
- A 1-year trial of repeated high-dose intravenous iron isomaltoside 1000 to maintain stable hemoglobin levels in inflammatory bowel disease.Scandinavian journal of gastroenterology · 2015Trial
- Efficacy and safety of IV ferumoxytol for adults with iron deficiency anemia previously unresponsive to or unable to tolerate oral iron.American journal of hematology · 2014Trial
- A randomized, open-label, non-inferiority study of intravenous iron isomaltoside 1,000 (Monofer) compared with oral iron for treatment of anemia in IBD (PROCEED).The American journal of gastroenterology · 2013Trial
108 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron deficiency anaemia is one of the most common disorders in the world. Also, one third of inflammatory bowel disease (IBD) patients suffer from recurrent anaemia. Anaemia has significant impact on the quality of life of affected patients. Chronic fatigue, a frequent IBD symptom itself, is commonly caused by anaemia and may debilitate patients as much as abdominal pain or diarrhoea. Common therapeutic targets are the mechanisms behind anaemia of chronic disease and iron deficiency. It is our experience that virtually all patients with IBD associated anaemia can be successfully treated with a combination of iron sucrose and erythropoietin, which then may positively affect the misled immune response in IBD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.