Evidence map›Paper›PMID 15239836›Full record

ArticleGenome biology2004

Clustering analysis of SAGE data using a Poisson approach.

Li Cai, Haiyan Huang, Seth Blackshaw, Jun S Liu, Connie Cepko, Wing H Wong

Abstract readComparative StudyValidation Study
In one paragraph

Article in Genome biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Li CaiDepartment of Biostatistics, Harvard School of Public Health, 66 Huntington Avenue, Boston, MA 02115, USA. lcai@research.dfci.harvard.edu
Haiyan Huang
Seth Blackshaw
Jun S Liu
Connie Cepko
Wing H Wong

Funding

MOLECULAR BIOLOGY OF RETINAL DEVELOPMENTR01EY008064 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI CEPKO, CONSTANCE L · 1989 to 2013
$4.0M
Computational Haplotype Analysis for SNPsR01HG002518 · NHGRI · HARVARD UNIVERSITY · PI LIU, JUN S · 2002 to 2010
$2.5M
Center for Computational Study of Biological SystemsP20CA096470 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LIU, JUN S · 2002 to 2004
$2.1M
NCI NIH HHS P20 CA096470NCI NIH HHS P20 CA96470NEI NIH HHS EY08064NEI NIH HHS R01 EY008064NHGRI NIH HHS R01 HG002518NHGRI NIH HHS R01 HG02518-01
6 · The paper itself

Abstract

Serial analysis of gene expression (SAGE) data have been poorly exploited by clustering analysis owing to the lack of appropriate statistical methods that consider their specific properties. We modeled SAGE data by Poisson statistics and developed two Poisson-based distances. Their application to simulated and experimental mouse retina data show that the Poisson-based distances are more appropriate and reliable for analyzing SAGE data compared to other commonly used distances or similarity measures such as Pearson correlation or Euclidean distance.

Indexed as

AnimalsAnimals, NewbornChromosome MappingCluster AnalysisComputer SimulationGene Expression ProfilingGene LibraryMiceModels, StatisticalPoisson DistributionRetinaSensitivity and Specificity

Identifiers

PMID15239836
PMCPMC463327

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.