Evidence map›Paper›PMID 15237088›Full record

ArticleBMJ (Clinical research ed.)2004

Does access to cardiac investigation and treatment contribute to social and ethnic differences in coronary heart disease? Whitehall II prospective cohort study.

Annie Britton, Martin Shipley, Michael Marmot, Harry Hemingway

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005680 (Whitehall II - Social and Occupational Influences On Health and Illness), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00005680 completednot on this map

Whitehall II - Social and Occupational Influences On Health and Illness

TypeobservationalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran1993 to 2007ConditionsCardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Ischemia
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Multiple Socioeconomic Circumstances and Initiation of Cardiovascular Medication among Ageing Employees.International journal of environmental research and public health · 2021
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  7. Observational
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  10. Effect of ethnicity on the prevalence, severity, and management of COPD in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Annie BrittonInternational Centre for Health and Society, Department of Epidemiology and Public Health, University College London Medical School, London WC1E 6BT.
Martin Shipley
Michael Marmot
Harry Hemingway
University College London · GB

Funding

CHANGES IN HEALTH: SOCIO-ECONOMIC STATUS AND PATHWAYSR37AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G · 1999 to 2008
$4.3M
Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
SOCIAL FACTORS INFLUENCING MEDICAL OUTCOME MEASURESR01HS006516 · AHRQ · UNIVERSITY OF LONDON · PI MARMOT, MICHAEL G · 1990 to 1995
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AHRQ HHS HS06516Medical Research Council G0100222Medical Research Council G19/35Medical Research Council G8802774NHLBI NIH HHS HL36310NIA NIH HHS AG13196
6 · The paper itself

Abstract

objectiveTo determine whether access to cardiac procedures and drugs contributes to social and ethnic differences in coronary heart disease in a population setting.

designProspective study with follow up over 15 years. Civil service employment grade was used as a measure of individual socioeconomic position. Need for cardiac care was determined by the presence of angina, myocardial infarction, and coronary risk factors.

setting20 civil service departments originally located in London.

participants10,308 civil servants (3414 women; 560 South Asian) aged 35-55 years at baseline in 1985-8.

main outcome measuresUse of exercise electrocardiography, coronary angiography, and coronary revascularisation procedures and secondary prevention drugs.

resultsInverse social gradients existed in incident coronary morbidity and mortality. South Asian participants also had higher rates than white participants. After adjustment for clinical need, social position showed no association with the use of cardiac procedures or secondary prevention drugs. For example, men in the low versus high employment grade had an age adjusted odds ratio for angiography of 1.87 (95% confidence interval 1.32 to 2.64), which decreased to 1.27 (0.83 to 1.94) on adjustment for clinical need. South Asians tended to be more likely to have cardiac procedures and to be taking more secondary prevention drugs than white participants, even after adjustment for clinical need.

conclusionThis population based study, which shows the widely observed social and ethnic patterning of coronary heart disease, found no evidence that low social position or South Asian ethnicity was associated with lower use of cardiac procedures or drugs, independently of clinical need. Differences in medical care are unlikely to contribute to social or ethnic differences in coronary heart disease in this cohort.

Indexed as

Health Services AccessibilityAdultCohort StudiesCoronary AngiographyCoronary DiseaseElectrocardiographyFemaleHumansMaleMiddle AgedMyocardial RevascularizationPrognosisProportional Hazards ModelsProspective StudiesRisk FactorsSocioeconomic FactorsEmpirical ApproachHealth Care and Public Health

Identifiers

PMID15237088
PMCPMC506850
OpenAlexW1990594417

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.