ArticleBMC genomics2004
A chloroplast-localized vesicular transport system: a bio-informatics approach.
Article in BMC genomics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 62 citations in OpenAlex.
- Thylakostasis: key factors in thylakoid membrane organization with emphasis on biogenesis and remodeling proteins in vascular plants.Plant & cell physiology · 2025Review
- Genome-wide identification and functional analysis of PEL gene family in Brassica napus L.BMC plant biology · 2025Article
- Stack-VTP: prediction of vesicle transport proteins based on stacked ensemble classifier and evolutionary information.BMC bioinformatics · 2023Article
- A Sec14 domain protein is required for photoautotrophic growth and chloroplast vesicle formation inProceedings of the National Academy of Sciences of the United States of America · 2020Article
- A brief history of thylakoid biogenesis.Open biology · 2019Review
- Computational identification of vesicular transport proteins from sequences using deep gated recurrent units architecture.Computational and structural biotechnology journal · 2019Article
- Chloroplast vesicle transport.Photosynthesis research · 2018Review
- IM30 triggers membrane fusion in cyanobacteria and chloroplasts.Nature communications · 2015Article
- A novel chloroplast localized Rab GTPase protein CPRabA5e is involved in stress, development, thylakoid biogenesis and vesicle transport in Arabidopsis.Plant molecular biology · 2014Article
- Article
- The puzzle of chloroplast vesicle transport - involvement of GTPases.Frontiers in plant science · 2014Review
- Bioinformatic indications that COPI- and clathrin-based transport systems are not present in chloroplasts: an Arabidopsis model.PloS one · 2014Article
- Article
- The first α-helical domain of the vesicle-inducing protein in plastids 1 promotes oligomerization and lipid binding.Planta · 2013Article
- Homologs of the yeast Tvp38 vesicle-associated protein are conserved in chloroplasts and cyanobacteria.Frontiers in plant science · 2013Article
- Article
- Review
- Evidence for the involvement of the Arabidopsis SEC24A in male transmission.Journal of experimental botany · 2011Article
- Biogenesis of thylakoid networks in angiosperms: knowns and unknowns.Plant molecular biology · 2011Review
- Genes co-expressed with CPSAR1 identified using ATTED-II.Plant signaling & behavior · 2010Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe thylakoid membrane of higher plant chloroplasts is made of membrane lipids synthesized in the chloroplast envelope. As the inner envelope membrane and the thylakoid are separated by the aqueous stroma, a system for transporting newly synthesized lipids from the inner envelope membrane to the thylakoid is required. Ultrastructural as well as biochemical studies have indicated that lipid transport inside the chloroplast could be mediated by a system similar in characteristics to vesicular trafficking in the cytosol. If indeed the chloroplast system is related to cytosolic vesicular trafficking systems, a certain degree of sequence conservation between components of the chloroplast and the cytosolic systems could be expected. We used the Arabidopsis thaliana genome and web-based subcellular localization prediction tools to search for chloroplast-localized homologues of cytosolic vesicular trafficking components.
resultsOut of the 28952 hypothetical proteins in the A. thaliana genome sequence, 1947 were predicted to be chloroplast-localized by two different subcellular localization predictors. In this chloroplast protein dataset, strong homologues for the main coat proteins of COPII coated cytosolic vesicles were found. Homologues of the small GTPases ARF1 and Sar1 were also found in the chloroplast protein dataset.
conclusionOur database search approach gives further support to that a system similar to cytosolic vesicular trafficking is operational inside the chloroplast. However, solid biochemical data is needed to support the chloroplast localization of the identified proteins as well as their involvement in intra-chloroplast lipid trafficking.
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