ArticlePlant physiology2004
Down-regulation of metallothionein, a reactive oxygen scavenger, by the small GTPase OsRac1 in rice.
Article in Plant physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 1 of them a synthesis that pooled it.
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Who cites it
130 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- The OsRhoGAP2-OsRAC5 complex regulates rice seed germination via modulating aleurone layer development and α-amylase activity.Plant cell reports · 2026Article
- Comprehensive Profiling of the RicePlants (Basel, Switzerland) · 2026Article
- OsMT2b Regulates Pollen Development and ROS Homeostasis in a Photoperiod-Dependent Manner.Plant biotechnology journal · 2026Article
- Fulvic Acid Suppresses Excessive Cytokinin Biosynthesis to Reduce ROS Content and thus Decrease NaRice (New York, N.Y.) · 2026Article
- The role of aerenchymatous gas spaces in root sodium ion management under salt stress: do they matter in rice?Annals of botany · 2025Article
- Single-cell transcriptomic analyses reveal cellular and molecular patterns of rose petal responses to gray mold infection.Horticulture research · 2025Article
- Comprehensive Identification of Key Genes Responsible for Leaf Senescence of Rice (Plants (Basel, Switzerland) · 2025Article
- Melatonin-Mediated Regulation of Antioxidant Defense Enhances the Resistance of Tea Plants (Plants (Basel, Switzerland) · 2025Article
- The Usefulness of physiological and biochemical stress response of soil collembola (Xenylla welchi Folsom, 1916) as a biomarker in a lead-amended garden soil.Environmental analysis, health and toxicology · 2025Article
- Differential gene expression in ripe mango fruit (Frontiers in fungal biology · 2025Article
- Involvement of the Metallothionein gene OsMT2b in Drought and Cadmium Ions Stress in Rice.Rice (New York, N.Y.) · 2024Article
- Heat-stress-induced ROS in maize silks cause late pollen tube growth arrest and sterility.iScience · 2024Article
- Abnormal Degraded Tapetum 1 (ADT1) is required for tapetal cell death and pollen development in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Reactive Oxygen and Related Regulatory Factors Involved in Ethylene-Induced Petal Abscission in Roses.Plants (Basel, Switzerland) · 2024Article
- Cloning and Functional Analysis of CsROP5 and CsROP10 Genes Involved in Cucumber Resistance toBiology · 2024Article
- Magnaporthe oryzae effector AvrPik-D targets a transcription factor WG7 to suppress rice immunity.Rice (New York, N.Y.) · 2024Article
- Metallothionein family genes in kiwifruit: characterization and determining their roles in plant's response to different stresses.Frontiers in plant science · 2024Article
- Emerging role of small GTPases and their interactome in plants to combat abiotic and biotic stress.Protoplasma · 2023Review
- Genome-wide analysis of the metallothionein gene family in cassava reveals its role in response to physiological stress through the regulation of reactive oxygen species.BMC plant biology · 2023Article
70 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metallothioneins are small, ubiquitous Cys-rich proteins known to be involved in reactive oxygen species (ROS) scavenging and metal homeostasis. We found that the expression of a metallothionein gene (OsMT2b) was synergically down-regulated by OsRac1 and rice (Oryza sativa) blast-derived elicitors. Transgenic plants overexpressing OsMT2b showed increased susceptibility to bacterial blight and blast fungus. OsMT2b-overexpressing cells showed reduced elicitor-induced hydrogen peroxide production. In contrast, homozygous OsMT2b::Tos17-inserted mutant and OsMT2b-RNAi-silenced transgenic cells showed significantly higher elicitor-induced hydrogen peroxide production than the wild-type cells. In vitro assay showed that recombinant OsMT2b protein possessed superoxide- and hydroxyl radical-scavenging activities. Taken together, these results showed that OsMT2b is an ROS scavenger and its expression is down-regulated by OsRac1, thus potentiating ROS, which function as signals in resistance response. The results suggest that OsRac1 plays a dual role as an inducer of ROS production and a suppressor of ROS scavenging.
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