Evidence map›Paper›PMID 15220377›Full record

ArticleJournal of clinical pathology2004

High molecular weight caldesmon positive stromal cells in the capsule of hepatocellular carcinomas.

H Nakayama, H Enzan, M Yamamoto, E Miyazaki, W Yasui

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical pathology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Hepatocellular Carcinoma: State of the Art Imaging and Recent Advances.Journal of clinical and translational hepatology · 2019
    Review
  3. Article
  4. Overexpression of progesterone receptor B increases sensitivity of human colon muscle cells to progesterone.American journal of physiology. Gastrointestinal and liver physiology · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

H NakayamaDepartment of Molecular Pathology, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan. nakayamh@hiroshima-u.ac.jp
H Enzan
M Yamamoto
E Miyazaki
W Yasui
Hiroshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo investigate the smooth muscle nature of the stromal cells in the capsule of hepatocellular carcinomas.

methodsImmunohistochemical analysis using monoclonal antibody to high molecular weight caldesmon (HCD), a highly specific marker for smooth muscle cells, was performed in 33 encapsulated hepatocellular carcinomas and adjacent hepatic tissues.

resultsHCD positive stromal cells were detected in the capsule of 21 of the 33 hepatocellular carcinomas examined.

conclusionsThe capsule of hepatocellular carcinomas contains smooth muscle cells.

Indexed as

Antibodies, MonoclonalCalmodulin-Binding ProteinsCarcinoma, HepatocellularHumansLiver NeoplasmsMolecular WeightMuscle, SmoothNeoplasm ProteinsStromal CellsAntibodies, MonoclonalCalmodulin-Binding ProteinsNeoplasm Proteins

Identifiers

PMID15220377
PMCPMC1770372
OpenAlexW2107337269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.