ArticleNucleic acids research2004
CHOP: parsing proteins into structural domains.
Article in Nucleic acids research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Approaches for the Identification of Intrinsically Disordered Protein Domains.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Protein domain identification methods and online resources.Computational and structural biotechnology journal · 2021Review
- Family-Specific Gains and Losses of Protein Domains in the Legume and Grass Plant Families.Evolutionary bioinformatics online · 2020Article
- The Proteome Folding Project: proteome-scale prediction of structure and function.Genome research · 2011Article
- Using context to improve protein domain identification.BMC bioinformatics · 2011Article
- Huntingtin facilitates polycomb repressive complex 2.Human molecular genetics · 2010Article
- A universal strategy for high-yield production of soluble and functional clostridial collagenases in E. coli.Applied microbiology and biotechnology · 2009Article
- Structural genomics is the largest contributor of novel structural leverage.Journal of structural and functional genomics · 2009Article
- Studying the folding of multidomain proteins.HFSP journal · 2008Article
- An insulin-like modular basis for the evolution of glucose transporters (GLUT) with implications for diabetes.Evolutionary bioinformatics online · 2007Article
- Natively unstructured loops differ from other loops.PLoS computational biology · 2007Article
- EVEREST: automatic identification and classification of protein domains in all protein sequences.BMC bioinformatics · 2006Article
- DIAL: a web-based server for the automatic identification of structural domains in proteins.Nucleic acids research · 2005Article
- NMPdb: Database of Nuclear Matrix Proteins.Nucleic acids research · 2005Article
- Sequence-based prediction of protein domains.Nucleic acids research · 2004Article
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Authors and funding
2 authors.
Funding
Abstract
Sequence-based domain assignment is one of the most important and challenging problems in structural biology. We have developed a method, CHOP, that chops proteins into domain-like fragments. The basic idea is to cut proteins from entirely sequenced organisms beginning from very reliable experimental information (Protein Data Bank), proceeding to expert annotations of domain-like regions (Pfam-A) and completing through cuts based on termini of native protein ends. The CHOP server takes protein sequences as input and returns the dissections supported by homology transfer. CHOP results are precompiled for many entirely sequenced proteomes. The service is available at http://www.rostlab.org/services/CHOP/.
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Registered trials
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