Evidence map›Paper›PMID 15215389›Full record

ArticleNucleic acids research2004

ConSite: web-based prediction of regulatory elements using cross-species comparison.

Albin Sandelin, Wyeth W Wasserman, Boris Lenhard

Abstract read
In one paragraph

Article in Nucleic acids research, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 220 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
220citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

220 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  9. Floral Development onPlants (Basel, Switzerland) · 2023
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  17. Alzheimer's Disease-Associated SNP rs708727 inInternational journal of molecular sciences · 2022
    Article
  18. Variants Within GenesFrontiers in genetics · 2022
    Article
  19. Current genomics · 2021
    Article
  20. Article

160 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Albin SandelinCenter for Genomics and Bioinformatics, Karolinska Institutet, Berzelius väg 35, s-17177 Stockholm, Sweden.
Wyeth W Wasserman
Boris Lenhard

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ConSite is a user-friendly, web-based tool for finding cis-regulatory elements in genomic sequences. Predictions are based on the integration of binding site prediction generated with high-quality transcription factor models and cross-species comparison filtering (phylogenetic footprinting). By incorporating evolutionary constraints, selectivity is increased by an order of magnitude as compared to single-sequence analysis. ConSite offers several unique features, including an interactive expert system for retrieving orthologous regulatory sequences. Programming modules and biological databases that form the foundation of the ConSite service are freely available to the research community. ConSite is available at http:/www.phylofoot.org/consite.

Indexed as

Regulatory Sequences, Nucleic AcidSoftwareAnimalsBinding SitesConserved SequenceDNADNA FootprintingInternetPhylogenySequence AlignmentSequence Analysis, DNATranscription FactorsDNATranscription Factors

Identifiers

PMID15215389
PMCPMC441510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.