ArticleAntimicrobial agents and chemotherapy2004
In vitro effects of resveratrol on the viability and infectivity of the microsporidian Encephalitozoon cuniculi.
Article in Antimicrobial agents and chemotherapy, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 37 citations in OpenAlex.
- Anti-blastocystosis activity of antioxidant coated ZIF-8 combined with mesoporous silicas MCM-41 and KIT-6.Scientific reports · 2022Article
- IsFrontiers in veterinary science · 2021Article
- Application of mass spectrometry to elucidate the pathophysiology of Encephalitozoon cuniculi infection in rabbits.PloS one · 2017Article
- Flow cytometry analysis of Nosema species to assess spore viability and longevity.Parasitology research · 2014Article
- Hydrogenosome metabolism is the key target for antiparasitic activity of resveratrol against Trichomonas vaginalis.Antimicrobial agents and chemotherapy · 2013Article
- Differences in the in vitro susceptibility to resveratrol and other chemical compounds among several Philasterides dicentrarchi isolates from turbot.Parasitology research · 2012Article
- Polyphenols and aging.Current aging science · 2010Review
- In vitro effects of resveratrol on Trichinella spiralis.Parasitology research · 2009Article
- In vitro antileishmanial activity of resveratrol and its hydroxylated analogues against Leishmania major promastigotes and amastigotes.Parasitology research · 2007Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microsporidians of the genus Encephalitozoon are an important cause of disease in immunocompromised patients, and there are currently no completely effective treatments. The present study investigated the viability and infectivity of spores of Encephalitozoon cuniculi that had been exposed to resveratrol (RESV), a natural phytoalexin found in grapes and red wine. RESV at 50 microM showed significant sporicidal activity, and at 10 to 50 microM it reduced the capacity of the spores to infect dog kidney epithelial cells of the MDCK line. At 10 microM RESV also significantly inhibited intracellular development of the parasite, without affecting host cell viability. These results suggest that RESV may be useful in the treatment of Encephalitozoon infections.
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Registered trials
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