ReviewAnnals of surgery2004
The diminishing role of surgery in the treatment of gastric lymphoma.
Review in Annals of surgery, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.
- Surgical treatment of primitive gastro-intestinal lymphomas: a systematic review.World journal of surgical oncology · 2011Pooled it
- Chlorambucil versus observation after anti-Helicobacter therapy in gastric MALT lymphomas: results of the international randomised LY03 trial.British journal of haematology · 2009Trial
- Long-term clinical outcomes of mediastinal lymphoma after surgical resection: reassessing the role of surgery.Journal of thoracic disease · 2025Article
- [Gastrointestinal mucosa-associated lymphoma].Innere Medizin (Heidelberg, Germany) · 2024Article
- Gastric Non-Hodgkin Lymphoma in aACG case reports journal · 2024Article
- A dynamic predictive nomogram of long-term survival in primary gastric lymphoma: a retrospective study.BMC gastroenterology · 2022Article
- Review
- Involved-site radiotherapy for Helicobacter pylori-independent gastric MALT lymphoma: 26 years of experience with 178 patients.Blood advances · 2021Article
- Pattern of failure and optimal treatment strategy for primary gastric diffuse large B-cell lymphoma treated with R-CHOP chemotherapy.PloS one · 2020Article
- Clinicopathological Features, Treatment Strategy, and Prognosis of Primary Non-Hodgkin's Lymphoma of the Duodenum: A SEER Database Analysis.Canadian journal of gastroenterology & hepatology · 2020Article
- Favorable radiation field decrease in gastric marginal zone lymphoma : Experience of the German Study Group on Gastrointestinal Lymphoma (DSGL).Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019Article
- Observational
- Gastric Mucormycosis Masquerading as Gastric Malignancy.Indian journal of surgical oncology · 2017Article
- Radiotherapy for localized gastric mucosa-associated lymphoid tissue lymphoma: long-term outcomes over 10 years.Journal of radiation research · 2017Article
- Clinical characteristics and prognostic factors of primary gastric lymphoma: A retrospective study with 165 cases.Medicine · 2016Observational
- Anatomic distribution, clinical features, and survival data of 87 cases primary gastrointestinal lymphoma.World journal of surgical oncology · 2016Article
- Colonic mucosa-associated lymphoid tissue lymphoma identified by chromoendoscopy.World journal of gastroenterology · 2014Article
- Helicobacter pylori infection in gastric mucosa-associated lymphoid tissue lymphoma.World journal of gastroenterology · 2014Review
- Clinicopathological characteristics and prognostic factors of primary gastrointestinal lymphoma: a 22-year experience from South China.International journal of clinical and experimental pathology · 2014Article
- Primary non-hodgkin lymphoma of the stomach: clinicopathological characteristics and prognostic factors in Iranian patients.Iranian journal of cancer prevention · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis article reviews the pathogenesis, diagnosis, and treatment of patients with primary gastric lymphoma, with special attention to the changing role of surgery. SUMMARY BACKGROUND DATA: Primary gastric lymphomas are non-Hodgkin lymphomas that originate in the stomach and are divided into low-grade (or indolent) and high-grade (or aggressive) types. Low-grade lesions nearly always arise from mucosa-associated lymphoid tissue (MALT) secondary to chronic Helicobacter pylori (H. pylori) infection and disseminate slowly. High-grade lesions may arise from a low grade-MALT component or arise de novo and can spread to lymph nodes, adjacent organs and tissues, or distant sites.
methodsA review of the relevant English-language articles was performed on the basis of a MEDLINE search from January 1984 to August 2003.
resultsAbout 40% of gastric lymphomas are low-grade, and nearly all these low-grade lesions are classified as MALT lymphomas. For low-grade MALT lymphomas confined to the gastric wall and without certain negative prognostic factors, H. pylori eradication is highly successful in causing lymphoma regression. More advanced low-grade lymphomas or those that do not regress with antibiotic therapy can be treated with combinations of H. pylori eradication, radiation therapy, and chemotherapy. Nearly 60% of gastric lymphomas are high-grade lesions with or without a low-grade MALT component. These lymphomas can be treated with chemotherapy and radiation therapy according to the extent of disease. Surgery for gastric lymphoma is now often reserved for patients with localized, residual disease after nonsurgical therapy or for rare patients with complications.
conclusionThe treatment of gastric lymphoma continues to evolve, and surgical resection is now uncommonly a part of the initial management strategy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.