ArticleInfection and immunity2004
Identification of a point mutation resulting in loss of cell wall anchoring activity of SrtA of Streptococcus mutans NG5.
Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Diversity of SpaP in genetic and salivary agglutinin mediated adherence among Streptococcus mutans strains.Scientific reports · 2019Article
- [Link between sortase A function and cariogenicity of Streptococcus mutans: a preliminary metabolomics analysis].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2018Article
- Effect of SrtA on Interspecies Adherence of Oral Bacteria.Current medical science · 2018Article
- In silico identification of potential inhibitors targeting Streptococcus mutans sortase A.International journal of oral science · 2017Article
- Effects of missense mutations in sortase A gene on enzyme activity in Streptococcus mutans.BMC oral health · 2016Article
- Genetic polymorphisms of the sortase A gene and social-behavioural factors associated with caries in children: a case-control study.BMC oral health · 2015Article
- Sortases and the art of anchoring proteins to the envelopes of gram-positive bacteria.Microbiology and molecular biology reviews : MMBR · 2006Review
- Genotypic diversity of Streptococcus mutans in children with and without early childhood caries- A systematic review.Journal of oral biology and craniofacial researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Streptococcus mutans NG5 failed to anchor antigen P1 to the cell surface, and such a failure could be attributed to a defective SrtA, which was made defective by a point mutation within the srtA gene. Without a functional SrtA, S. mutans NG5 was not able to perform a number of cell surface-related activities, including saliva-mediated adherence and aggregation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.