ArticleInfection and immunity2004
Function of the fibronectin-binding serum opacity factor of Streptococcus pyogenes in adherence to epithelial cells.
Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 37 citations in OpenAlex.
- What makes them stick? A genetic analysis of biofilm formation of an infective endocarditis-causingFrontiers in cellular and infection microbiology · 2026Article
- Discovery of a new fibronectin-binding surface protein ofFrontiers in cellular and infection microbiology · 2026Article
- Interplay between group AMicrobiology and molecular biology reviews : MMBR · 2024Review
- Review
- The group A streptococcal collagen-like protein-1, Scl1, mediates biofilm formation by targeting the extra domain A-containing variant of cellular fibronectin expressed in wounded tissue.Molecular microbiology · 2013Article
- Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.Journal of bacteriology · 2012Article
- Superantigen profiles of emm and emm-like typeable and nontypeable pharyngeal streptococcal isolates of South India.Annals of clinical microbiology and antimicrobials · 2012Article
- Apolipoprotein E mediates enhanced plasma high-density lipoprotein cholesterol clearance by low-dose streptococcal serum opacity factor via hepatic low-density lipoprotein receptors in vivo.Arteriosclerosis, thrombosis, and vascular biology · 2011Article
- A processed multidomain mycoplasma hyopneumoniae adhesin binds fibronectin, plasminogen, and swine respiratory cilia.The Journal of biological chemistry · 2010Article
- The structure and function of serum opacity factor: a unique streptococcal virulence determinant that targets high-density lipoproteins.Journal of biomedicine & biotechnology · 2010Review
- Apolipoprotein modulation of streptococcal serum opacity factor activity against human plasma high-density lipoproteins.Biochemistry · 2009Article
- Serum opacity factor is a streptococcal receptor for the extracellular matrix protein fibulin-1.The Journal of biological chemistry · 2009Article
- Avian pathogenic Escherichia coli bind fibronectin and laminin.Veterinary research communications · 2009Article
- Opacification Domain of Serum Opacity Factor Inhibits Beta-Hemolysis and Contributes to Virulence ofmSphereArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The serum opacity factor (SOF) of Streptococcus pyogenes is a serotyping tool and pathogenesis factor. Using SOF-coated latex beads in cell adherence assays and antiserum directed against SOF in S. pyogenes-HEp-2 cell adherence inhibition experiments, we demonstrate SOF involvement in the fibronectin-mediated adherence of S. pyogenes to epithelial cells. SOF exclusively targets the 30-kDa N-terminal region of fibronectin. The interaction revealed association and dissociation constants 1 order of magnitude lower than those of other S. pyogenes fibronectin-binding proteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.