ArticleInfection and immunity2004
Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis.
Article in Infection and immunity, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Profiling the host defense responses againstmLife · 2026Article
- A genetic screen in Drosophila reveals the role of fucosylation in host susceptibility to Candida infection.Disease models & mechanisms · 2022Article
- Glucose metabolism and glycosylation link the gut microbiota to autoimmune diseases.Frontiers in immunology · 2022Review
- Microbial lectome versus host glycolipidome: How pathogens exploit glycosphingolipids to invade, dupe or kill.Frontiers in microbiology · 2022Review
- Maternal H-antigen secretor status is an early biomarker for potential preterm delivery.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens.PLoS pathogens · 2020Article
- Advances in Understanding Human Genetic Variations That Influence Innate Immunity to Fungi.Frontiers in cellular and infection microbiology · 2020Review
- Infection's Sweet Tooth: How Glycans Mediate Infection and Disease Susceptibility.Trends in microbiology · 2018Review
- Histo-blood group antigens as receptors for rotavirus, new understanding on rotavirus epidemiology and vaccine strategy.Emerging microbes & infections · 2017Review
- Human Gut Microbiota: Toward an Ecology of Disease.Frontiers in microbiology · 2017Review
- Epithelial glycosylation in gut homeostasis and inflammation.Nature immunology · 2016Review
- Pathogenic role of the gut microbiota in gastrointestinal diseases.Intestinal research · 2016Review
- The Role of IL-22 in Viral Infections: Paradigms and Paradoxes.Frontiers in immunology · 2016Article
- Article
- Blood Groups in Infection and Host Susceptibility.Clinical microbiology reviews · 2015Review
- Innate lymphoid cells regulate intestinal epithelial cell glycosylation.Science (New York, N.Y.) · 2014Article
- Faecal microbiota composition in adults is associated with the FUT2 gene determining the secretor status.PloS one · 2014Article
- Isolation of bifidobacteria for blood group secretor status targeted personalised nutrition.Microbial ecology in health and disease · 2012Article
- Secretor genotype (FUT2 gene) is strongly associated with the composition of Bifidobacteria in the human intestine.PloS one · 2011Article
- Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.Human molecular genetics · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fut2-LacZ-null mice, which are a model of the human ABO and Lewis nonsecretor group, display increased susceptibility to experimental yeast vaginitis, indicating a role for alpha(1,2)fucosylated cervical glycans in mucosal defense. However, the lack of significant effect of competitive inhibition by exogenous neoglycoproteins in this study emphasizes the complexity of Candida-epithelial cell adhesion events.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.