ArticleLipids in health and disease2004
The effects of antioxidant vitamin supplementation on resistance exercise induced lipid peroxidation in trained and untrained participants.
Article in Lipids in health and disease, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Royal jelly plus coenzyme Q10 supplementation improves high-intensity interval exercise performance via changes in plasmatic and salivary biomarkers of oxidative stress and muscle damage in swimmers: a randomized, double-blind, placebo-controlled pilot trial.Journal of the International Society of Sports Nutrition · 2022Trial
- Tomato powder is more effective than lycopene to alleviate exercise-induced lipid peroxidation in well-trained male athletes: randomized, double-blinded cross-over study.Journal of the International Society of Sports Nutrition · 2021Trial
- The Effect of one-week spinach and NBS superfood supplementation on interleukin-6, superoxide dismutase, and malondialdehyde levels after repeated bouts of wingate test in trained men.Nutrition & metabolism · 2025Article
- Exploring the Relationship between Micronutrients and Athletic Performance: A Comprehensive Scientific Systematic Review of the Literature in Sports Medicine.Sports (Basel, Switzerland) · 2023Review
- Oregano (Nutrients · 2022Article
- Effects of resistance training and turmeric supplementation on reactive species marker stress in diabetic rats.BMC sports science, medicine & rehabilitation · 2020Article
- Exercise-Induced Oxidative Stress and the Effects of Antioxidant Intake from a Physiological Viewpoint.Antioxidants (Basel, Switzerland) · 2018Review
- Oxidative stress and antioxidant responses to progressive resistance exercise intensity in trained and untrained males.Biology of sport · 2015Article
- The effect of an acute antioxidant supplementation compared with placebo on performance and hormonal response during a high volume resistance training session.Journal of the International Society of Sports Nutrition · 2014Article
- Protective effect of a hydroethanolic extract from Bowdichia virgilioides on muscular damage and oxidative stress caused by strenuous resistance training in rats.Journal of the International Society of Sports Nutrition · 2014Article
- Antioxidant supplementation during exercise training: beneficial or detrimental?Sports medicine (Auckland, N.Z.) · 2011Review
- Ectopic catalase expression in mitochondria by adeno-associated virus enhances exercise performance in mice.PloS one · 2009Article
- Acute exercise and oxidative stress: a 30 year history.Dynamic medicine : DM · 2009Article
- Prior exercise and antioxidant supplementation: effect on oxidative stress and muscle injury.Journal of the International Society of Sports Nutrition · 2007Article
- Effects of different resistance exercise protocols on nitric oxide, lipid peroxidation and creatine kinase activity in sedentary males.Journal of sports science & medicine · 2007Article
- Vitamin E supplementation, exercise and lipid peroxidation in human participants.European journal of applied physiology · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe theoretical benefits of using antioxidant vitamin supplements to quench oxygen free radicals appear large. High intensity aerobic-type exercise produces oxygen free radicals that can cause damage to lipid membranes (lipid peroxidation) that may lead to many problems such as the inactivation of cell membrane enzymes, the progression of degenerative diseases (cardiovascular disease and cancer) and lessening of the effectiveness of the immune system. The major function of vitamin E is to work as a chain-breaking antioxidant in a fat soluble environment. Little research has examined lipid peroxidation associated with high intensity resistance exercise or possible protective effects of antioxidant supplementation or the effects of training state.
resultsThere were no significant group (trained vs untrained) or treatment (vitamin E vs placebo) effects found between the 4 groups assessed. There was only one significant difference found and that was in the main effect for time (F = 22.41, p < 0.01).
conclusionsThe Resistance Exercise Test caused a significant increase in malondialdehyde in all 4 groups at 6 hours post exercise. There was no evidence that vitamin E supplementation was effective in reducing oxidative damage in comparison to the placebo group. As well, there was no difference between the trained and untrained groups with respect to their impact on lipid peroxidation measures.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.