ArticleProceedings of the National Academy of Sciences of the United States of America2004
Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- The minor spliceosome component U4atac regulates JAK/STAT signaling to modulate hematopoiesis and immune responses in Drosophila melanogaster.Nature communications · 2026Article
- RNA-binding protein Miso/CG44249 is crucial for minor splicing during oogenesis inRNA (New York, N.Y.) · 2025Article
- Minor Spliceosomal 65K/RNPC3 Interacts with ANKRD11 and Mediates HDAC3-Regulated Histone Deacetylation and Transcription.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Defective minor spliceosomes induce SMA-associated phenotypes through sensitive intron-containing neural genes in Drosophila.Nature communications · 2020Article
- Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.G3 (Bethesda, Md.) · 2015Article
- Evolutionarily divergent spliceosomal snRNAs and a conserved non-coding RNA processing motif in Giardia lamblia.Nucleic acids research · 2012Article
- Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathways.PloS one · 2010Article
- Ribonucleoprotein multimers and their functions.Critical reviews in biochemistry and molecular biology · 2010Review
- Evolutionary dynamics of U12-type spliceosomal introns.BMC evolutionary biology · 2010Article
- Genetic screen in Drosophila melanogaster uncovers a novel set of genes required for embryonic epithelial repair.Genetics · 2010Article
- Evolution of spliceosomal snRNA genes in metazoan animals.Journal of molecular evolution · 2008Article
- Minor spliceosome components are predominantly localized in the nucleus.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- U12DB: a database of orthologous U12-type spliceosomal introns.Nucleic acids research · 2007Article
- Quantification of ortholog losses in insects and vertebrates.Genome biology · 2007Article
- Spliceosomal small nuclear RNA genes in 11 insect genomes.RNA (New York, N.Y.) · 2007Article
- The abundance of the spliceosomal snRNPs is not limiting the splicing of U12-type introns.RNA (New York, N.Y.) · 2006Article
- Comprehensive splice-site analysis using comparative genomics.Nucleic acids research · 2006Article
- Evolutionary conservation of minor U12-type spliceosome between plants and humans.RNA (New York, N.Y.) · 2005Article
- Proximity of the U12 snRNA with both the 5' splice site and the branch point during early stages of spliceosome assembly.Molecular and cellular biology · 2005Article
- The significant other: splicing by the minor spliceosome.Wiley interdisciplinary reviews. RNAReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous reports suggested that U11, in contrast to U12 or other small nuclear (sn)RNAs of the U12-type spliceosome, might be either highly divergent or absent in Drosophila melanogaster. Affinity purification of Drosophila U12-containing complexes has led to the identification of the fly U11 snRNA, which contains a potential U12-type 5' splice-site-interacting sequence, but whose sequence and length differs significantly from vertebrate and plant U11. Analysis of U12-type introns revealed an A-rich region directly downstream of Drosophila, but not human, U12-type 5' splice sites. This finding, coupled with the presence of a highly divergent U11 snRNA, and the apparent absence of Drosophila homologs of human U11 proteins, suggest that U12-type 5' splice site recognition might be different in flies. A comparison of U11 snRNAs that we have identified from vertebrates, plants, and insects, suggests that an evolutionarily divergent U11 snRNA may be unique to Drosophila and not characteristic of insects in general.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.