ArticleThe Plant cell2004
A multidrug resistance-associated protein involved in anthocyanin transport in Zea mays.
Article in The Plant cell, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers.
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186 citing papers in PubMed, 429 citations in OpenAlex.
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- Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation.BMC genomics · 2026Article
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- Mapped deletions in a publicly available Fast Neutron mutant collection for gene identification in pea.BMC plant biology · 2026Article
- Overexpression of a Tonoplast Malate Transporter Gene Leads to Enhanced Anthocyanin Biosynthesis in Apple.Plant biotechnology journal · 2026Article
- Comparative transcriptomics of anthocyanin accumulation in the pericarp of pigmented purple corn.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Tissue-specific profiles of phenolic metabolites in rice deprived ofFrontiers in plant science · 2026Article
- The vacuolar transporters MaMATE11 and MaMATE14 affect blue flower coloration in grape hyacinth (Horticulture research · 2026Article
- Unraveling the genetic and molecular mechanisms of anthocyanin biosynthesis and accumulation in maize kernels.Frontiers in plant science · 2026Review
- Diversity and ecological functions of anthocyanins.BMC plant biology · 2025Review
- De novo transcriptome analysis and functional annotation of Silybum Marianum L. under drought stress with a focus on Silymarin synthesis and MAPK signaling pathways.BMC plant biology · 2025Article
- Genome-Wide Identification of ATP-Binding Cassette (ABC) Transporter Gene Family and Their Expression Analysis in Response to Anthocyanin Transportation in the Fruit Peel of Eggplant (International journal of molecular sciences · 2025Article
- Comparative transcriptomics of atrazine-tolerant and sensitive alfalfa varieties under atrazine stress.BMC plant biology · 2025Article
- Recent advances in biosynthesis and regulation of strawberry anthocyanins.Horticulture research · 2025Article
- The PpAHL17-PpHYH module is involved in light-independent anthocyanin accumulation in fruit peel of Prunus persica.Plant cell reports · 2025Article
- Weighted gene co-expression network analysis - based selection of hub genes related to phenolic and volatile compounds and seed coat color in sorghum.BMC plant biology · 2025Article
- Analysis of rabbiteye blueberry metabolomes and transcriptomes reveals mechanisms underlying potassium-induced anthocyanin production.Scientific reports · 2025Article
- Anthocyanin metabolites and related regulatory genes analysis in leaves of Acer Pseudosieboldianum mutant during different periods of color change.BMC genomics · 2025Article
- Transcriptomic and targeted metabolomic analysis identifies genes involved in differential anthocyanin accumulation in potato tubers.Frontiers in plant science · 2025Article
126 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anthocyanin biosynthesis is one of the most thoroughly studied enzymatic pathways in biology, but little is known about the molecular mechanisms of its final stage: the transport of the anthocyanin pigment into the vacuole. We have identified a multidrug resistance-associated protein (MRP), ZmMrp3, that is required for this transport process in maize (Zea mays). ZmMrp3 expression is controlled by the regulators of anthocyanin biosynthesis and mirrors the expression of other anthocyanin structural genes. Localization of ZmMRP3 in vivo shows its presence in the tonoplast, the site at which anthocyanin transport occurs. Mutants generated using antisense constructs have a distinct pigmentation phenotype in the adult plant that results from a mislocalization of the pigment as well as significant reduction in anthocyanin content, with no alteration in the anthocyanin species produced. Surprisingly, mutant plants did not show a phenotype in the aleurone. This appears to reflect the presence of a second, highly homologous gene, ZmMrp4, that is also coregulated with the anthocyanin pathway but is expressed exclusively in aleurone tissue. This description of a plant MRP with a role in the transport of a known endogenous substrate provides a new model system for examining the biological and biochemical mechanisms involved in the MRP-mediated transport of plant secondary metabolites.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.