ArticleJournal of bacteriology2004
Sigma54 enhancer binding proteins and Myxococcus xanthus fruiting body development.
Article in Journal of bacteriology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Milestones in the development ofJournal of bacteriology · 2025Review
- Myxobacterial Genomics and Post-Genomics: A Review of Genome Biology, Genome Sequences and Related 'Omics Studies.Microorganisms · 2021Review
- Three PilZ Domain Proteins, PlpA, PixA, and PixB, Have Distinct Functions in Regulation of Motility and Development in Myxococcus xanthus.Journal of bacteriology · 2021Article
- Transcriptome dynamics of theeLife · 2019Article
- Spontaneous Reversions of an Evolutionary Trait Loss Reveal Regulators of a Small RNA That Controls Multicellular Development in Myxobacteria.Journal of bacteriology · 2016Article
- σ54-dependent regulome in Desulfovibrio vulgaris Hildenborough.BMC genomics · 2015Article
- Transcription factor MrpC binds to promoter regions of hundreds of developmentally-regulated genes in Myxococcus xanthus.BMC genomics · 2014Article
- A multifunctional enzyme is involved in bacterial ether lipid biosynthesis.Nature chemical biology · 2014Article
- Draft Genome Sequence of Myxococcus xanthus Wild-Type Strain DZ2, a Model Organism for Predation and Development.Genome announcements · 2013Article
- Structural mechanism of GAF-regulated σ(54) activators from Aquifex aeolicus.Journal of molecular biology · 2013Article
- Article
- The Nla28S/Nla28 two-component signal transduction system regulates sporulation in Myxococcus xanthus.Journal of bacteriology · 2012Article
- A cascade of coregulating enhancer binding proteins initiates and propagates a multicellular developmental program.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Comparative analyses imply that the enigmatic Sigma factor 54 is a central controller of the bacterial exterior.BMC genomics · 2011Article
- Global analysis of phase variation in Myxococcus xanthus.Molecular microbiology · 2011Article
- Article
- Identification of enhancer binding proteins important for Myxococcus xanthus development.Journal of bacteriology · 2010Article
- Lipid body formation plays a central role in cell fate determination during developmental differentiation of Myxococcus xanthus.Molecular microbiology · 2009Article
- Bioinformatics and experimental analysis of proteins of two-component systems in Myxococcus xanthus.Journal of bacteriology · 2008Article
- The Myxococcus xanthus Nla4 protein is important for expression of stringent response-associated genes, ppGpp accumulation, and fruiting body development.Journal of bacteriology · 2007Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
A search of the M1genome sequence, which includes 97% of the Myxococcus xanthus genes, identified 53 sequence homologs of sigma54-dependent enhancer binding proteins (EBPs). A DNA microarray was constructed from the M1genome that includes those homologs and 318 other M. xanthus genes for comparison. To screen the developmental program with this array, an RNA extract from growing cells was compared with one prepared from developing cells at 12 h. Previous reporter studies had shown that M. xanthus has initiated development and has begun to express many developmentally regulated genes by 12 h. The comparison revealed substantial increases in the expression levels of 11 transcription factors that may respond to environmental stimuli. Six of the 53 EBP homologs were expressed at significantly higher levels at 12 h of development than during growth. Three were previously unknown genes, and they were inactivated to look for effects on fruiting body development. One knockout mutant produced fruiting bodies of abnormal shape that depended on the composition of the medium.
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Registered trials
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