ArticleAJNR. American journal of neuroradiology
MR imaging in the diagnosis of desmoplastic infantile tumor: retrospective study of six cases.
Article in AJNR. American journal of neuroradiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed, 89 citations in OpenAlex.
- Imaging diagnosis of cystic intraparenchymal brain neoplasms.Japanese journal of radiology · 2026Review
- Desmoplastic infantile ganglioglioma and astrocytoma: A narrative review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Review
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- The molecular characteristics of low-grade and high-grade areas in desmoplastic infantile astrocytoma/ganglioglioma.Neuropathology and applied neurobiology · 2022Article
- Desmoplastic infantile astrocytoma and ganglioglioma: a series of 12 patients treated at a single institution.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Imaging of brain tumors in children: the basics-a narrative review.Translational pediatrics · 2021Review
- Multifocal Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIA/DIG): An Institutional Series Report and a Clinical Summary of This Rare Tumor.Frontiers in oncology · 2021Article
- Desmoplastic Infantile Ganglioglioma Masquerading as an Arachnoid Cyst.Oman medical journal · 2019Article
- Novel suprasellar location of desmoplastic infantile astrocytoma and ganglioglioma: a single institution's experience.Journal of neurosurgery. Pediatrics · 2018Article
- A Rare Tumor in Childhood Desmoplastic Infantile Astrocytoma: Two Case Reports.Sisli Etfal Hastanesi tip bulteni · 2018Article
- Atypical imaging in a desmoplastic non-infantile astrocytoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Progressive Disordered Movements in an Infant Leads to Rare Diagnosis.Clinical practice and cases in emergency medicine · 2017Article
- Perinatal (fetal and neonatal) astrocytoma: a review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Review
- Supratentorial tumors typical of the infantile age: desmoplastic infantile ganglioglioma (DIG) and astrocytoma (DIA). A review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Review
- Desmoplastic astrocytoma: new insights into its clinical profile, diagnosis, and treatment.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Review
- Diffusion, Perfusion, and Histopathologic Characteristics of Desmoplastic Infantile Ganglioglioma.Journal of radiology case reports · 2016Review
- Desmoplastic infantile astrocytoma with multiple intracranial and intraspinal localizations at presentation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Non-infantile variant of desmoplastic ganglioglioma: Conventional and advanced MR imaging characteristics.The neuroradiology journal · 2015Article
- MR imaging, apparent diffusion coefficient and histopathological features of desmoplastic infantile tumors-own experience and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeDesmoplastic infantile tumors (DITs) are rare supratentorial tumors of infancy with a favorable prognosis. Radiologic and histologic features of DIT are misleading, and DIT may be misinterpreted as a malignant lesion. We have studied the usefulness of MR imaging in the diagnosis of these tumors.
methodsBetween 1995 and 2002, six DITs were diagnosed in young children at our institution. Neuroimaging, age at diagnosis, sex, clinical presentation, symptoms duration, follow-up, and development were studied retrospectively. Contrast-enhanced CT and MR images were available. MR study included T1-, T2-, and postgadolinium T1-weighted sequences in the axial, sagittal, and coronal planes.
resultsThese tumors were massive and predominantly cystic, with preferential frontal and parietal involvement. Typically, a DIT appears as a hypointense cystic mass with an isointense peripheral solid component on T1-weighted MR images. The peripheral solid component enhances after gadolinium administration. On T2-weighted MR images, the cystic component is hyperintense and the solid portion isointense or heterogeneous. The cystic portion is usually located deep inside the lesion, whereas its solid portion is peripheral. Meningeal enhancement and thickening adjacent to the solid portion of the tumor, calcifications, bone abnormalities adjacent to the tumor consisting of thinning and deformation were noted in 50% of our cases. Edema was usually absent or moderate. Median follow-up was 32 months, and no recurrence was noted except for one atypical case with incomplete excision, which led to the patient's death.
conclusionDespite their malignant appearance, MR imaging features of DIT may help in the diagnosis and obviate unnecessary chemotherapy or radiation therapy.
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15205142PMC7975656W2130018651What OpenQuestion holds
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