Evidence map›Paper›PMID 15202071›Full record

ArticleAmerican journal of human genetics2004

A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa.

Barbara Arredi, Estella S Poloni, Silvia Paracchini, Tatiana Zerjal, Dahmani M Fathallah, Mohamed Makrelouf, Vincenzo L Pascali, Andrea Novelletto, Chris Tyler-Smith

Abstract read
In one paragraph

Article in American journal of human genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

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  11. Genetics and genomic medicine in Tunisia.Molecular genetics & genomic medicine · 2018
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Barbara ArrediIstituto di Medicina Legale, Università Cattolica del Sacro Cuore di Roma, Rome, Italy. b_arredi@libero.it
Estella S Poloni
Silvia Paracchini
Tatiana Zerjal
Dahmani M Fathallah
Mohamed Makrelouf
Vincenzo L Pascali
Andrea Novelletto
Chris Tyler-Smith

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have typed 275 men from five populations in Algeria, Tunisia, and Egypt with a set of 119 binary markers and 15 microsatellites from the Y chromosome, and we have analyzed the results together with published data from Moroccan populations. North African Y-chromosomal diversity is geographically structured and fits the pattern expected under an isolation-by-distance model. Autocorrelation analyses reveal an east-west cline of genetic variation that extends into the Middle East and is compatible with a hypothesis of demic expansion. This expansion must have involved relatively small numbers of Y chromosomes to account for the reduction in gene diversity towards the West that accompanied the frequency increase of Y haplogroup E3b2, but gene flow must have been maintained to explain the observed pattern of isolation-by-distance. Since the estimates of the times to the most recent common ancestor (TMRCAs) of the most common haplogroups are quite recent, we suggest that the North African pattern of Y-chromosomal variation is largely of Neolithic origin. Thus, we propose that the Neolithic transition in this part of the world was accompanied by demic diffusion of Afro-Asiatic-speaking pastoralists from the Middle East.

Indexed as

Chromosomes, Human, YEvolution, MolecularGenetic VariationAfrica, NorthernHumansMalePhylogeny

Identifiers

PMID15202071
PMCPMC1216069

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.