ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2004
Spontaneous separation of epiretinal membrane in young subjects: personal observations and review of the literature.
Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 84 citations in OpenAlex.
- Preexisting Fundus Findings in a Large Cohort of Young Cynomolgus Macaques (Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2026Article
- A Case of Self-Detachment of a Stage 3 Idiopathic Epiretinal Membrane Due to Posterior Vitreous Detachment.Cureus · 2025Article
- Spontaneous epiretinal membrane resolution: mechanisms, outcomes, and implications for clinical management.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- Clinical factors and predictors for spontaneous separation of epiretinal membranes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Spontaneous separation of secondary epiretinal membrane after vitrectomy for retinal detachment.American journal of ophthalmology case reports · 2024Article
- Comment on: Recurrence after spontaneous separation of epiretinal membrane in a young woman: a case report.International journal of ophthalmology · 2024Article
- Article
- Spontaneous Epiretinal Membrane Resolution and Angiotensin Receptor Blockers: Case Observation, Literature Review and Perspectives.Biomedicines · 2023Article
- Pars Plana Vitrectomy in Inherited Retinal Diseases: A Comprehensive Review of the Literature.Life (Basel, Switzerland) · 2023Review
- Recurrence after spontaneous separation of epiretinal membrane in a young woman: a case report.International journal of ophthalmology · 2023Article
- Epiretinal membrane after branch retinal vein occlusion: Separation after dexamethasone implant injection.American journal of ophthalmology case reports · 2022Article
- Photocoagulation-associated spontaneous release of epiretinal membrane secondary to retinal vascular tumor: case series of 8 cases.Lasers in medical science · 2022Article
- Vitrectomy in full thickness macular holes on top of a pigment epithelial detachment in age-related macular degeneration (AMD). Surgical consideration and review of the literature.American journal of ophthalmology case reports · 2021Article
- Rapid Morphological Restoration of Normal Foveal Contour After Spontaneous Epiretinal Membrane Separation from Retina in Eye with Macular Pseudohole: A Case Report.International medical case reports journal · 2021Article
- Long-term natural history of the idiopathic epiretinal membrane in children and young adults.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- An Unusual Case: Self-separation of an Idiopathic Epiretinal MembraneTurkish journal of ophthalmology · 2020Article
- Evaluation of Factors Affecting Epiretinal Membrane Surgery Outcomes.Beyoglu eye journal · 2019Article
- Microvascular changes after vitrectomy with internal limiting membrane peeling: an optical coherence tomography angiography study.International ophthalmology · 2018Article
- Long-term follow-up of lamellar macular holes and pseudoholes over at least 5 years.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018Article
- A white membrane beneath the inner limiting membrane of the retina in a 4-year-old child with ultrastructural evidence: a case report.BMC ophthalmology · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdiopathic epiretinal membranes (ERM) grow on the surface of the internal limiting membrane (ILM) and are a very uncommon condition in young subjects.
methodsWe report six young subjects with ERM and describe the spontaneous separation of the membranes. The functional and anatomical recovery was assessed by Snellen visual acuity, Amsler grid and funduscopy. Selected cases were additionally assessed by optical coherence tomography (OCT).
resultsAll subjects initially claimed a sudden, unilateral, reduction in visual acuity (VA) with severe distortion at the age of 15-30 years. No ocular trauma or disease was ascertained in any case. Initial fundus examination demonstrated a gray-whitish ERM with translucent stress lines over the macula. Visual recovery occurred in all cases after resolution of the ERM. Sequential OCT demonstrated the successive peeling of an ERM accompanied by normalization of foveal thickness.
conclusionsYoung subjects should be counseled about the favorable prognosis for maintaining good vision and possible spontaneous membrane separation. Conservative observation is advocated if the visual disturbance is located temporally, as functional recovery and spontaneous membrane separation may occur. When the contracting forces of the immature ERM are stronger than its adhesions to the retina, the membrane may separate spontaneously.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.