ArticleProceedings of the National Academy of Sciences of the United States of America2004
A plant plasma membrane Ca2+ pump is required for normal pollen tube growth and fertilization.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.
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Who cites it
140 citing papers in PubMed, 320 citations in OpenAlex.
- Molecular understanding of plant pollination, fertilization, seed development and protoplast regeneration.Science China. Life sciences · 2026Review
- Genome-Wide Identification of the CaPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Identification of the P-Type CaInternational journal of molecular sciences · 2026Article
- Genetic defects in the CDP-choline pathway for phosphatidylcholine biosynthesis cannot be transmitted to offspring via male gametophytes owing to interruption of autophagy-like processes required for pollen germination in Arabidopsis thaliana.Journal of plant research · 2026Article
- Integrated Omic Analyses Reveal Module Networks Regulating Growth and Bioactive Component Synthesis ofPlants (Basel, Switzerland) · 2026Article
- The endoplasmic reticulum-localized CaFrontiers in plant science · 2026Article
- Agent-based simulation of cortical microtubule band movement in arabidopsis zygotes.Scientific reports · 2025Article
- Identification of the ACA/ECA gene family and preliminary verification of their functional in calcium transport in lettuce.Scientific reports · 2025Article
- MID1-COMPLEMENTING ACTIVITY regulates cell proliferation and development via Ca2+ signaling in Marchantia polymorpha.Plant physiology · 2024Article
- Genome-Wide Identification and Expression Analysis ofInternational journal of molecular sciences · 2024Article
- Pollen-expressed RLCKs control pollen tube burst.Plant communications · 2024Article
- Understanding the role of P-type ATPases in regulating pollen fertility and development in pigeonpea.Molecular genetics and genomics : MGG · 2024Article
- Review
- From gametes to zygote: Mechanistic advances and emerging possibilities in plant reproduction.Plant physiology · 2024Review
- OsACA9, an Autoinhibited CaInternational journal of molecular sciences · 2024Article
- Rapid alkalinization factor: function, regulation, and potential applications in agriculture.Stress biology · 2023Review
- Resting cytosol Ca2+ level maintained by Ca2+ pumps affects environmental responses in Arabidopsis.Plant physiology · 2023Article
- Simple cryopreservation protocol forFrontiers in plant science · 2023Article
- DORN1 Is Involved in Drought Stress Tolerance through a CaInternational journal of molecular sciences · 2022Article
- Structure, Function, and Applications of Soybean Calcium Transporters.International journal of molecular sciences · 2022Review
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ca(2+) signals are thought to play important roles in plant growth and development, including key aspects of pollen tube growth and fertilization. The dynamics of a Ca(2+) signal are largely controlled by influx (through channels) and efflux (through pumps and antiporters). The Arabidopsis genome encodes 14 Ca(2+) pumps, 10 of which belong to a family of autoinhibited Ca(2+) ATPases (ACA) that are predicted to be activated by Ca(2+)/calmodulin. Here, we show that isoform ACA9 is expressed primarily in pollen and localized to the plasma membrane. Three independent T-DNA [portion of the Ti (tumor-inducing) plasmid that is transferred to plant cells] gene disruptions of ACA9 were found to result in partial male sterility. Complementation was observed by using a ACA9-yellow fluorescence protein (YFP) fusion that displayed plasma membrane localization. Mutant aca9 pollen displayed a reduced growth potential and a high frequency of aborted fertilization, resulting in a >80% reduction in seed set. These findings identify a plasma membrane Ca(2+) transporter as a key regulator of pollen development and fertilization in flowering plants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.