Evidence map›Paper›PMID 15196562›Full record

ReviewCurrent opinion in cell biology2004

Mechanics and regulation of cytokinesis.

Douglas N Robinson, James A Spudich

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Cleavage-furrow formation without F-actin inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  3. Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  4. Article
  5. Article
  6. Article
  7. Signaling networks that regulate cell migration.Cold Spring Harbor perspectives in biology · 2015
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Douglas N RobinsonDepartment of Cell Biology, Johns Hopkins University School of Medicine, 725 N. Wolfe St., Baltimore, MD 21205, USA.
James A Spudich

Funding

MYOSIN MOVEMENT IN VITRO: MOLECULAR CHARACTERIZATIONR01GM033289 · NIGMS · STANFORD UNIVERSITY · PI SPUDICH, JAMES · 1985 to 2024
$13.6M
The Biochemical Basis for the Mechanics of CytokinesisR01GM066817 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ROBINSON, DOUGLAS N · 2003 to 2025
$7.3M
Myosin-II Dynamics and CytokinesisR01GM046551 · NIGMS · STANFORD UNIVERSITY · PI SPUDICH, JAMES A · 2002 to 2005
$1.6M
REGULATION OF DICTYOSTELIUM MYOSIN BY PHOSPHORYLATIONR37GM046551 · NIGMS · STANFORD UNIVERSITY · PI SPUDICH, JAMES A · 1991 to 2000
$272k
NIGMS NIH HHS R01 GM033289NIGMS NIH HHS R01 GM046551NIGMS NIH HHS R01 GM066817NIGMS NIH HHS R01 GM46551NIGMS NIH HHS R37 GM046551Wellcome Trust
6 · The paper itself

Abstract

Recent advances are revealing quantitative aspects of cytokinesis. Further, genetic analyses and cell imaging are providing insights into the molecular dynamics of cleavage furrow ingression as well as further refining our knowledge of the zones of the mitotic spindle that regulate the contractile properties of the overlying cortex. Ultimately, however, cortical mechanics are the result of signals that emanate from the mitotic spindle. A genuine quantitative understanding of cytokinesis must include a thorough analysis of the mechanical properties of the cortex and how signals modify these properties to dictate a well-controlled, error-free cytokinesis.

Indexed as

Actin CytoskeletonAnimalsCytokinesisDictyosteliumHumansMicrotubulesMolecular Motor ProteinsMyosin Type IISignal TransductionSpindle ApparatusMolecular Motor ProteinsMyosin Type II

Identifiers

PMID15196562
PMCPMC7336204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.