ArticleThe Journal of physiology2004
Electrotonic coupling between stratum oriens interneurones in the intact in vitro mouse juvenile hippocampus.
Article in The Journal of physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 37 citations in OpenAlex.
- Article
- Structure and Functions of Gap Junctions and Their Constituent Connexins in the Mammalian CNS.Biochemistry (Moscow) Supplement. Series A, Membrane and cell biology · 2021Article
- Slow periodic activity in the longitudinal hippocampal slice can self-propagate non-synaptically by a mechanism consistent with ephaptic coupling.The Journal of physiology · 2019Article
- From Neuron Biophysics to Orientation Selectivity in Electrically Coupled Networks of Neocortical L2/3 Large Basket Cells.Cerebral cortex (New York, N.Y. : 1991) · 2016Article
- Gap junctions in developing thalamic and neocortical neuronal networks.Cerebral cortex (New York, N.Y. : 1991) · 2014Review
- Roles of gap junctions, connexins, and pannexins in epilepsy.Frontiers in physiology · 2014Review
- Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus.PloS one · 2014Article
- Transition to seizure: ictal discharge is preceded by exhausted presynaptic GABA release in the hippocampal CA3 region.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- High temperatures alter physiological properties of pyramidal cells and inhibitory interneurons in hippocampus.Frontiers in cellular neuroscience · 2012Article
- Gap junctions between interneurons are required for normal spatial coding in the hippocampus and short-term spatial memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Propagation of postsynaptic currents and potentials via gap junctions in GABAergic networks of the rat hippocampus.The Journal of physiology · 2007Article
- Interneuron and pyramidal cell interplay during in vitro seizure-like events.Journal of neurophysiology · 2006Article
- Electrical coupling between interneurons with different excitable properties in the stratum lacunosum-moleculare of the juvenile CA1 rat hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
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Authors and funding
3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Using the isolated juvenile (7-14 days) mouse whole hippocampus preparation, which contains intact complex local circuitry, 145 dual whole cell recordings were made from stratum oriens (s.o.) interneurones under infrared microscopy. In 11.7% of paired recordings, evidence for direct electrotonic coupling between the s.o. interneurones was obtained from the response of one interneurone to a long (400-600 ms) constant current pulse passed into the coupled interneurone. When specifically orienting the dual recordings in the transectional plane of the hippocampus, 18.5% of paired recordings showed electrotonic coupling. The coupling coefficient, estimated from averaged data, was 6.9 +/- 4.7%, ranging from 1.3 to 17.6%. The time constant of the electrotonically transmitted hyperpolarization was inversely related to the coupling coefficient between the two neurones. The electrotonic responses of one neurone to constant current pulses injected into the other coupled neurone were intermittent. Spikes in one of the coupled neurones were associated with small electrotonic EPSPs (spikelets) in the other coupled neurone, in those neuronal pairs with coupling coefficients greater than 10%. Failure of spikelet production following a spike in the coupled cell occurred 5-10% of the time. Electrotonic coupling and spikelets persisted in the presence of chemical synaptic transmission blockade by CNQX, APV and bicuculline, or in zero Ca(2+) perfusate, but were abolished by carbenoxolone (100 microm), a gap junctional blocker. These data confirm the existence of electrotonic coupling between s.o. interneurones, presumably via gap junctions located in dendrites.
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