Evidence map›Paper›PMID 15193760›Full record

ArticleNeuroscience letters2004

The role of Period1 in non-photic resetting of the hamster circadian pacemaker in the suprachiasmatic nucleus.

Toshiyuki Hamada, Michael C Antle, Rae Silver

Abstract read
In one paragraph

Article in Neuroscience letters, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Acute suppressive and long-term phase modulation actions of orexin on the mammalian circadian clock.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Toshiyuki HamadaAge Dimension Research Center, National Institute of Advanced Industrial Science and Technology, AIST Tsukuba Central 6th site 1-1-1, Higashi, Tsukuba, Ibaraki, 305-8562, Japan.
Michael C Antle
Rae Silver

Funding

PHYSIOLOGICAL DISSECTION OF THE SCNR01NS037919 · NINDS · BARNARD COLLEGE · PI SILVER, RAE · 1998 to 2010
$3.3M
NINDS NIH HHS NS37919NINDS NIH HHS R01 NS037919
6 · The paper itself

Abstract

Non-photic stimuli, such as diurnal wheel running in rodents, phase shift the circadian clock and suppress the expression of Per1 in the suprachiasmatic nucleus (SCN). The goal of the present study was to directly decrease Per1 expression using antisense (AS) oligodeoxynucleotides to determine if such suppression produced non-photic phase shifts. Injections of Per1-AS suppressed expression of Per1 within the SCN and produced phase shifts similar to those resulting from other non-photic manipulation, with large phase advances to injections during the subjective day. These results indicate that the decrease in expression of Per1 is a cause rather than a consequence of non-photic phase shifts.

Indexed as

AnimalsBiological ClocksCircadian RhythmCricetinaeMaleMesocricetusNuclear ProteinsOligodeoxyribonucleotides, AntisenseSuprachiasmatic NucleusNuclear ProteinsOligodeoxyribonucleotides, Antisense

Identifiers

PMID15193760
PMCPMC3275422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.