ArticleJournal of clinical microbiology2004
Simple, rapid latex agglutination test for serotyping of pneumococci (Pneumotest-Latex).
Article in Journal of clinical microbiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 118 citations in OpenAlex.
- Article
- Detection of Pneumococcal Carriage in Asymptomatic Healthcare Workers.Open forum infectious diseases · 2025Article
- Evaluation of Indigenous Latex Agglutination Assay based on Recombinant Pasteurella Lipoprotein E (rPlpE) As Antigen for Detection of AntiArchives of Razi Institute · 2024Article
- Article
- Comparison of next generation technologies and bioinformatics pipelines for capsular typing ofJournal of clinical microbiology · 2023Article
- Persistence of Pneumococcal Carriage among Older Adults in the Community despite COVID-19 Mitigation Measures.Microbiology spectrum · 2023Article
- The Molecular Approaches and Challenges ofPolish journal of microbiology · 2023Review
- Key features of pneumococcal isolates recovered in Central and Northwestern Russia in 2011-2018 determined through whole-genome sequencing.Microbial genomics · 2022Article
- Validation of Fourier Transform Infrared Spectroscopy for Serotyping of Streptococcus pneumoniae.Journal of clinical microbiology · 2022Article
- Self-Assembled Peptide-Labeled Probes for Agglutination-Based Sensing.Macromolecular research · 2021Article
- Identification of Streptococcus pneumoniae and other Mitis streptococci: importance of molecular methods.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Review
- Reduction of antimicrobial resistant pneumococci seven years after introduction of pneumococcal vaccine in Iceland.PloS one · 2020Article
- Investigation of Antibiotic Resistance, Serotype Distribution, and Genetic Characteristics of 164 InvasiveInfection and drug resistance · 2020Article
- Streptococcus pneumoniae Acquisition and Carriage in Vaccine Naïve Indian Children with HIV and their Parents: A Longitudinal Household Study.Indian journal of pediatrics · 2019Article
- Epidemiology of invasive pneumococcal disease in indigenous and non-indigenous adults in northwestern Ontario, Canada, 2006-2015.BMC infectious diseases · 2018Observational
- Serotypes & penicillin susceptibility ofThe Indian journal of medical research · 2018Article
- Molecular Characterization of Pneumococcal Surface Protein A (PspA), Serotype Distribution and Antibiotic Susceptibility of Streptococcus pneumoniae Strains Isolated from Pakistan.Infectious diseases and therapy · 2018Article
- Pneumococcal Nasopharyngeal Carriage in Young Healthy Children After Pneumococcal Conjugate Vaccine in Turkey.Balkan medical journal · 2017Article
- Group B Streptococcus among Pregnant Women and Newborns in Mirzapur, Bangladesh: Colonization, Vertical Transmission, and Serotype Distribution.Journal of clinical microbiology · 2017Observational
- Phenotypic and molecular study of pneumococci causing respiratory tract infections. A 3-year prospective cohort.Saudi medical journal · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The "gold standard" for epidemiological typing of Streptococcus pneumoniae (pneumococcus) is the capsular reaction test (Neufeld test) with antisera against the 90 pneumococcal polysaccharide capsules, i.e., serotyping. The method is labor intensive and requires a certain level of experience to be performed satisfactory, and thus it has been restricted for use in specialized reference or research laboratories. Surveillance of the serotype distribution of pneumococci that cause infections is important to secure an optimal composition of pneumococcal vaccines and to monitor antibiotic resistance in pneumococci. At Statens Serum Institut, a simple latex agglutination test for serotyping of pneumococci has been developed. The Pneumotest-Latex kit consists of 14 different pooled pneumococcus antisera (pools A to I and pools P to T) applied to latex particles. In a blind test of 352 isolates (with all 90 serotypes represented), 336 (95.5%) were typed or grouped correctly by the Pneumotest-Latex; in addition, 2 (7%) of 30 strains regarded as nontypeable or rough strains were serotyped, and the serotypes of these two isolates were confirmed by the capsular reaction test with type-specific antisera. The Pneumotest-Latex seems to be a sensitive method for serotyping or grouping of the majority of pneumococcal strains. By use of this ready-to-perform latex agglutination kit (Pneumotest-Latex), serotyping of pneumococci can gain more ground as a tool in prevention of pneumococcal diseases.
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Registered trials
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