Evidence map›Paper›PMID 15183773›Full record

ArticleAnalytical biochemistry2004

Nanogold-plasmon-resonance-based glucose sensing.

Kadir Aslan, Joseph R Lakowicz, Chris D Geddes

Abstract read
In one paragraph

Article in Analytical biochemistry, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Noninvasive Glucose Sensing In Vivo.Sensors (Basel, Switzerland) · 2023
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. A combined spectroscopic andRSC advances · 2020
    Article
  9. Article
  10. Article
  11. Chemisorption of iodine-125 to gold nanoparticles allows for real-time quantitation and potential use in nanomedicine.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2017
    Article
  12. Article
  13. Review
  14. Article
  15. Nanomaterial-mediated Biosensors for Monitoring Glucose.Journal of diabetes science and technology · 2014
    Review
  16. Article
  17. Review
  18. Detection of quadruplex DNA by gold nanoparticles.Journal of analytical methods in chemistry · 2012
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kadir AslanInstitute of Fluorescence, Medical Biotechnology Center, University of Maryland Biotechnology Institute, 725 West Lombard St, Baltimore, MD 21201, USA.
Joseph R Lakowicz
Chris D Geddes

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI BASKAKOV, ILIA V · 1993 to 2006
$7.4M
NCRR NIH HHS P41 RR008119NCRR NIH HHS RR-08119
6 · The paper itself

Abstract

Noble metal nanoparticles are well known for their strong interactions with light through the resonant excitations of the collective oscillations of the conduction electrons on the particles, the so-called surface plasmon resonances. The close proximity of two nanoparticles is known to result in a red-shifted resonance wavelength peak, due to near-field coupling. We have subsequently employed this phenomenon and developed a new approach to glucose sensing, which is based on the aggregation and disassociation of 20-nm gold particles and the changes in plasmon absorption induced by the presence of glucose. High-molecular-weight dextran-coated nanoparticles are aggregated with concanavalin A (Con A), which results in a significant shift and broadening of the gold plasmon absorption. The addition of glucose competitively binds to Con A, reducing gold nanoparticle aggregation and therefore the plasmon absorption when monitored at a near-red arbitrary wavelength. We have optimized our plasmonic-type glucose nanosensors with regard to particle stability, pH effects, the dynamic range for glucose sensing, and the observation wavelength to be compatible with clinical glucose requirements and measurements. In addition, by modifying the amount of dextran or Con A used in nanoparticle fabrication, we can to some extent tune the glucose response range, which means that a single sensing platform could potentially be used to monitor microM --> mM glucose levels in many physiological fluids, such as tears, blood, and urine, where the glucose concentrations are significantly different.

Indexed as

Biosensing TechniquesConcanavalin ADextransGlucoseGoldNanostructuresSensitivity and SpecificitySurface Plasmon ResonanceConcanavalin ADextransGlucoseGold

Identifiers

PMID15183773
PMCPMC6986337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.