ReviewDrugs & aging2004
Over-the-counter analgesics in older adults: a call for improved labelling and consumer education.
Review in Drugs & aging, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.
- Analgesic use and risk of renal cell carcinoma: A case-control, cohort and meta-analytic assessment.International journal of cancer · 2016Pooled it
- Trial
- Knowledge, attitudes, and practices of pharmacists toward over-the-counter medication use in Iraq: a nationwide cross-sectional study.Frontiers in pharmacology · 2025Article
- The landscape of self-care in Australia: A pharmacy perspective.Exploratory research in clinical and social pharmacy · 2024Article
- A pill as a quick solution: association between painkiller intake, empathy, and prosocial behavior.Scientific reports · 2023Article
- Self-medication with over-the-counter drugs among consumers: a cross-sectional survey in a Southwestern State in Nigeria.BMJ open · 2023Article
- Observational case-control study of small-fiber neuropathies, with regards on smoking and vitamin D deficiency and other possible causes.Frontiers in medicine · 2022Article
- Perspectives on Using Fast-Dissolving Paracetamol for Mild-to-Moderate Pain Management in Elderly or Diabetic Patients with Delayed Gastric Emptying Rates: An Exploratory Study.Journal of pain research · 2022Article
- Azole Fungicides and Their Endocrine Disrupting Properties: Perspectives on Sex Hormone-Dependent Reproductive Development.Frontiers in toxicology · 2022Review
- Utilizing a cognitive engineering approach to conduct a hierarchical task analysis to understand complex older adult decision-making during over-the-counter medication selection.Research in social & administrative pharmacy : RSAP · 2021Article
- A Scoping Review of Non-Medical and Extra-Medical Use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).Drug safety · 2021Article
- Polypharmacy and Potential Drug-Drug Interactions in Home-Dwelling Older People - A Cross-Sectional Study.Journal of multidisciplinary healthcare · 2021Article
- A pilot study of decision factors influencing over-the-counter medication selection and use by older adults.Research in social & administrative pharmacy : RSAP · 2020Article
- Staff perceptions of prescription and over-the-counter drug dependence services in England: a qualitative study.Addiction science & clinical practice · 2019Article
- Comorbid Zolpidem Dependence and Over-the-Counter Compound Analgesic Abuse.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2019Article
- Development of a Theory-Based Intervention to Enhance Information Exchange during Over-The-Counter Consultations in Community Pharmacy.Pharmacy (Basel, Switzerland) · 2018Article
- Nonsteroidal Anti-Inflammatory Drugs and Analgesics Use by Kidney Transplant Recipients.Annals of transplantation · 2018Article
- Quality improvement of community pharmacy services: a prioritisation exercise.The International journal of pharmacy practice · 2018Article
- Estimating Consumers' Knowledge and Attitudes Towards Over-The-Counter Analgesic Medication in Greece in the Years of Financial Crisis: The Case of Paracetamol.Pain and therapy · 2016Article
- Prevalence, trends, patterns and associations of analgesic use in Germany.BMC pharmacology & toxicology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of analgesics increases with age and on any given day 20-30% of older adults take an analgesic medication. Over-the-counter (OTC) analgesics are generally well tolerated and effective when taken for brief periods of time and at recommended dosages. However, their long-term use, use at inappropriately high doses, or use by persons with contraindications may result in adverse effects, including gastrointestinal haemorrhage, cardiovascular toxicity, renal toxicity and hepatotoxicity. Many OTC drugs are also available through a prescription, for a broader range of indications and for longer durations of use and wider dose ranges, under the assumption that healthcare providers will help patients make safe choices about analgesics. Safe and effective use of medications is one of the greatest challenges faced by healthcare providers in medicine. More than 60% of people cannot identify the active ingredient in their brand of pain reliever. Additionally, about 40% of Americans believe that OTC drugs are too weak to cause any real harm. As a result of a recent US FDA policy, the conversion of prescription to OTC medications will result in a 50% increase of OTC medications. To reduce the risks of potential adverse effects from OTC drug therapy in older adults, we propose that the use of analgesics will be enhanced through the use of patient and healthcare provider education, as well as improved labelling of OTC analgesics. Improved labelling of OTC analgesics may help consumers distinguish common analgesic ingredients in a wide variety of preparations and facilitate informed decisions concerning the use of OTC drugs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.