ArticleJournal of bacteriology2004
Control of photosynthetic and high-light-responsive genes by the histidine kinase DspA: negative and positive regulation and interactions between signal transduction pathways.
Article in Journal of bacteriology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 75 citations in OpenAlex.
- Article
- Gene expression and organization of thylakoid protein complexes in the PSII-less mutant ofPlant direct · 2022Article
- Mutations in hik26 and slr1916 lead to high-light stress tolerance in Synechocystis sp. PCC6803.Communications biology · 2021Article
- The Journey from Two-Step to Multi-Step Phosphorelay Signaling Systems.Current genomics · 2021Review
- Stress Signaling in Cyanobacteria: A Mechanistic Overview.Life (Basel, Switzerland) · 2020Review
- We're in this Together: Sensation of the Host Cell Environment by Endosymbiotic Bacteria.Results and problems in cell differentiation · 2020Article
- Light-inducible expression of translation factor EF-Tu during acclimation to strong light enhances the repair of photosystem II.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Universal Molecular Triggers of Stress Responses in CyanobacteriumLife (Basel, Switzerland) · 2019Review
- Translating Divergent Environmental Stresses into a Common Proteome Response through the Histidine Kinase 33 (Hik33) in a Model Cyanobacterium.Molecular & cellular proteomics : MCP · 2017Article
- Regulation of the scp Genes in the Cyanobacterium Synechocystis sp. PCC 6803--What is New?Molecules (Basel, Switzerland) · 2015Article
- Glutaredoxins are essential for stress adaptation in the cyanobacterium Synechocystis sp. PCC 6803.Frontiers in plant science · 2013Article
- RpaA regulates the accumulation of monomeric photosystem I and PsbA under high light conditions in Synechocystis sp. PCC 6803.PloS one · 2012Article
- Acclimation to high-light conditions in cyanobacteria: from gene expression to physiological responses.Journal of plant research · 2012Review
- Stress sensors and signal transducers in cyanobacteria.Sensors (Basel, Switzerland) · 2010Review
- Chloroplast two-component systems: evolution of the link between photosynthesis and gene expression.Proceedings. Biological sciences · 2009Review
- The high light-inducible polypeptides stabilize trimeric photosystem I complex under high light conditions in Synechocystis PCC 6803.Plant physiology · 2008Article
- Responses of a thermophilic Synechococcus isolate from the microbial mat of Octopus Spring to light.Applied and environmental microbiology · 2007Article
- NblA gene expression in Synechocystis PCC 6803 strains lacking DspA (Hik33) and a NblR-like protein.Current microbiology · 2007Article
- Cyanobacterial two-component proteins: structure, diversity, distribution, and evolution.Microbiology and molecular biology reviews : MMBR · 2006Review
- The influence of acetyl phosphate on DspA signalling in the Cyanobacterium Synechocystis sp. PCC6803.BMC microbiology · 2005Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have deleted a gene for a sensor histidine kinase, dspA (or hik33), in the cyanobacterium Synechocystis sp. strain PCC6803. In low and moderate light, the mutant grew slowly under photoautotrophic conditions, with a doubling time of approximately 40 h, and had severely reduced photosynthetic oxygen evolution. When the mutant was maintained in low or moderate light in the presence of glucose, its growth rate was only somewhat lower than that of wild-type cells. However, the mutant was light sensitive and rapidly died in high light. Furthermore, levels of many transcripts encoding genes associated with photosynthesis were altered in the mutant relative to wild-type Synechocystis sp. strain PCC6803 both in low light and following exposure to high light. There was constitutive expression of several high-light-inducible genes, including hli, psbAIII, and gpx2; there was little increased accumulation of sodB mRNA in high light; and the cells failed to accumulate cpcBA and psaAB mRNAs in low light in the presence of glucose, although a normal decline in the levels of these mRNAs was observed during exposure to high light. These results suggest that DspA is involved in controlling sets of photosynthetic and high-light-responsive genes, either directly or indirectly. These and other results, some of which are presented in a companion paper (C.-J. Tu, J. Shrager, R. Burnap, B. L. Postier, and A. R. Grossman, J. Bacteriol. 186:3889-3902, 2004), suggest that DspA acts as a global regulator that helps coordinate cellular metabolism with growth limitations imposed by environmental conditions.
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