ArticleEnvironmental health perspectives2004
Breast cancer risk and historical exposure to pesticides from wide-area applications assessed with GIS.
Article in Environmental health perspectives, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 89 citations in OpenAlex.
- Studying the impact of early life exposures to pesticides on the risk of testicular germ cell tumors during adulthood (TESTIS project): study protocol.BMC cancer · 2014Trial
- Case study application of high-throughput new approach methodologies for exposure to the interpretation of matched biomarker and indoor media measurements.Journal of exposure science & environmental epidemiology · 2026Article
- Modern sources of controls in case-control studies.American journal of epidemiology · 2025Article
- Comprehensive Nontargeted Analysis of Drinking Water Supplies to Identify Chemicals Associated with Estrogen Receptor Agonism or Present in Regions of Elevated Breast Cancer Occurrence.Environmental science & technology · 2025Article
- Geospatial Modeling Methods in Epidemiological Kidney Research: An Overview and Practical Example.Kidney international reports · 2024Review
- Evaluating the accuracy of satellite-based methods to estimate residential proximity to agricultural crops.Journal of exposure science & environmental epidemiology · 2024Article
- Introduction to the Special Issue ofInternational journal of environmental research and public health · 2022Article
- A case-control study of breast cancer risk and ambient exposure to pesticides.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
- Inequality of female health and its relation with urbanization level in China: geographic variation perspective.Environmental science and pollution research international · 2019Article
- Accuracy of two geocoding methods for geographic information system-based exposure assessment in epidemiological studies.Environmental health : a global access science source · 2017Article
- Aerial pesticide application causes DNA damage in pilots from Sinaloa, Mexico.Environmental science and pollution research international · 2017Article
- Associations between residence at birth and mental health disorders: a spatial analysis of retrospective cohort data.BMC public health · 2015Article
- Spatio-temporal analysis of female breast cancer incidence in Shenzhen, 2007-2012.Chinese journal of cancer · 2015Article
- Exposure to fogger trucks and breast cancer incidence in the Long Island Breast Cancer Study Project: a case-control study.Environmental health : a global access science source · 2013Article
- Inequalities in cancer distribution in tehran; a disaggregated estimation of 2007 incidencea by 22 districts.International journal of preventive medicine · 2012Article
- The effect of administrative boundaries and geocoding error on cancer rates in California.Spatial and spatio-temporal epidemiology · 2012Article
- Self-reported chemicals exposure, beliefs about disease causation, and risk of breast cancer in the Cape Cod Breast Cancer and Environment Study: a case-control study.Environmental health : a global access science source · 2010Article
- Self-reported exposure to pesticides in residential settings and risk of breast cancer: a case-control study.Environmental health : a global access science source · 2010Article
- The Pine River statement: human health consequences of DDT use.Environmental health perspectives · 2009Review
- Spatial analysis of bladder, kidney, and pancreatic cancer on upper Cape Cod: an application of generalized additive models to case-control data.Environmental health : a global access science source · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Pesticides are of interest in etiologic studies of breast cancer because many mimic estrogen, a known breast cancer risk factor, or cause mammary tumors in animals, but most previous studies have been limited by using one-time tissue measurements of residues of only a few pesticides long banned in the United States. As an alternative method to assess historical exposures to banned and current-use pesticides, we used geographic information system (GIS) technology in a population-based case-control study of 1,165 women residing in Cape Cod, Massachusetts, who were diagnosed with breast cancer in 1988-1995 and 1,006 controls. We assessed exposures dating back to 1948 (when DDT was first used there) from pesticides applied for tree pests (e.g., gypsy moths), cranberry bogs, other agriculture, and mosquito control on wetlands. We found no overall pattern of association between pesticide use and breast cancer. We found modest increases in risk associated with aerial application of persistent pesticides on cranberry bogs and less persistent pesticides applied for tree pests or agriculture. Adjusted odds ratios for these exposures were 1.8 or lower, and, with a few exceptions, confidence intervals did not exclude the null. The study is limited by uncertainty about locations of home addresses (particularly before 1980) and unrecorded tree pest and mosquito control events as well as lack of information about exposures during years when women in the study lived off Cape Cod and about women with potentially important early life exposures on Cape Cod who were not included because they moved away.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.