Evidence map›Paper›PMID 15175148›Full record

ReviewCurrent allergy and asthma reports2004

Ocular allergy treatment comparisons: azelastine and olopatadine.

Leonard Bielory, Praveen Buddiga, Stephen Bigelson

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 12 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Leonard BieloryDepartment of Medicine & Pediatric Ophthalmology, UMDNJ-New Jersey Medical School, Newark, 07103, USA. bielory@umdnj.edu
Praveen Buddiga
Stephen Bigelson
University Hospital, Newark · USRutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Azelastine hydrochloride 0.05% and olopatadine hydrochloride 0.1% are topical ocular allergy treatments that have demonstrated multiple pharmacologic actions, including antihistamine, mast cell stabilization, and inhibition of proinflammatory mediators. In this article, the mechanisms of action, efficacy, and tolerability of these two agents on ocular signs and symptoms are examined. By studying the various target sites of drug action, an enhanced clinical response algorithm of these topical ocular agents can be implemented to maximize the response for patients suffering from ocular allergy.

Indexed as

Administration, TopicalAnti-Allergic AgentsAnti-Inflammatory Agents, Non-SteroidalClinical Trials as TopicConjunctivitis, AllergicDibenzoxepinsHistamine H1 AntagonistsHistamine H2 AntagonistsHumansMast CellsOlopatadine HydrochloridePhthalazinesAnti-Allergic AgentsAnti-Inflammatory Agents, Non-SteroidalazelastineDibenzoxepinsHistamine H1 AntagonistsHistamine H2 AntagonistsOlopatadine HydrochloridePhthalazines

Identifiers

PMID15175148
OpenAlexW2041462997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.