ArticleJournal of clinical pathology1992
IgA antibody response during acquired and congenital toxoplasmosis.
Article in Journal of clinical pathology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 106 citations in OpenAlex.
- Assessment of simultaneous IgM, IgG avidity, and IgA testing in diagnosis of acute toxoplasmosis in pregnant women: a systematic review and meta-analysis study.BMC pregnancy and childbirth · 2025Pooled it
- The global seroprevalence of anti-Toxoplasma gondii antibodies in women who had spontaneous abortion: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2020Pooled it
- Classification system and case definitions of Toxoplasma gondii infection in immunocompetent pregnant women and their congenitally infected offspring. European Research Network on Congenital Toxoplasmosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 1996Guideline
- Will we miss specific IgA detection for the diagnosis of congenital toxoplasmosis? A French retrospective monocenter study on 483 infants.Journal of clinical microbiology · 2025Article
- The Trivalent Recombinant Chimeric Proteins Containing Immunodominant Fragments ofInternational journal of molecular sciences · 2025Article
- Cord blood IgA/M reveals in utero response to SARS-CoV-2 with fluctuations in relation to circulating variants.Nature communications · 2025Article
- In defense of children's brain: reshuffling the laboratory toolbox for the diagnosis of congenital toxoplasmosis.Journal of clinical microbiology · 2024Article
- Effective factors in the pathogenesis ofHeliyon · 2024Review
- Disturbances in the IgG Antibody Profile in HIV-Exposed Uninfected Infants Associated with Maternal Factors.Journal of immunology research · 2024Article
- Diagnosis of Congenital Toxoplasmosis: No Benefit of IgA Antibody Detection by Platelia ELISA in a Tricentric Evaluation.Journal of clinical microbiology · 2022Article
- Research on demographic, clinical and paraclinical aspects in pregnant women infected withExperimental and therapeutic medicine · 2022Article
- Serum IgA Antibodies Specific toFrontiers in medicine · 2021Article
- Seroprevalence and Risk Factors ofInfectious diseases in obstetrics and gynecology · 2021Article
- Role ofJournal of clinical microbiology · 2019Article
- Toxoplasma gondii infections among pregnant women, children and HIV-seropositive persons in Accra, Ghana.Tropical medicine and health · 2016Article
- Pediatric uveitis: An update.Oman journal of ophthalmology · 2013Review
- Laboratory support in the diagnosis of uveitis.Indian journal of ophthalmology · 2013Review
- Sero-epidemiology of toxoplasmosis amongst pregnant women in the greater accra region of ghana.Ghana medical journal · 2009Article
- Serological Screening of Newborns forEJIFCC · 2007Article
- Strategy for diagnosis of congenital toxoplasmosis: evaluation of methods comparing mothers and newborns and standard methods for postnatal detection of immunoglobulin G, M, and A antibodies.Journal of clinical microbiology · 2001Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Toxoplasma gondii specific IgA and IgM antibodies were quantitated by an antibody capture agglutination assay in 260 patients with acquired toxoplasmosis and from 94 fetuses suspected of congenital toxoplasmosis and 30 infected children. In acquired toxoplasmosis, IgA antibodies to T gondii were found in 95% of the cases. In congenital toxoplasmosis IgA antibodies were more frequently detected (75%) in cord blood than IgM antibodies (61%). They persisted after birth, in some cases for up to 24 months. IgA antibodies were also detected in fetuses whose mothers had toxoplasmosis during their pregnancy. In infected fetuses IgM and IgA antibodies were detected in fetal blood as early as week 24 of pregnancy. Detection of IgA T gondii antibodies may be useful for the diagnosis of some recently acquired infection and for the diagnosis and follow up of the infection in the fetus and neonate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.