Evidence map›Paper›PMID 15172021›Full record

ArticleEuropean journal of internal medicine2004

The common cold: a review of the literature.

Dennis Wat

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in European journal of internal medicine, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04103099 (Evaluation of the Impact of the HLNatural, Inc. Immune Support Product in Reducing the Length of Cold Symptoms in Adults Suffering From the Common Cold), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04103099 nacompletednot on this mapstarted 2019, after this paper: background citation

Evaluation of the Impact of the HLNatural, Inc. Immune Support Product in Reducing the Length of Cold Symptoms in Adults Suffering From the Common Cold

TypeinterventionalSponsorHawthorne Effect Inc.Ran2019 to 2020Enrolled200ConditionsImmune System DiseasesArmsHLNatural Immune
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.

  1. Oral antihistamine-decongestant-analgesic combinations for the common cold.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Vaccines for the common cold.The Cochrane database of systematic reviews · 2017
    Pooled it
  3. Effects of creating a non-specific, virus-hostile environment in the nasopharynx on symptoms and duration of common cold.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2007
    Trial
  4. Article
  5. Article
  6. Observational
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  9. Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Infection of primary nasal epithelial cells differentiates among lethal and seasonal human coronaviruses.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. In Vitro Antiviral and Anti-Inflammatory Activities ofInternational journal of molecular sciences · 2023
    Article
  19. Article
  20. PhytoestrogenVaccines · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Dennis WatCystic Fibrosis Unit, Department of Child Health, University Hospital of Wales, Heath Park, CF14 4XW, UK.
University Hospital of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory viral infections, also known as the common cold, are the most common infections in humans. Despite their benign nature, they are a major cause of morbidity and mortality on a worldwide basis. Several viruses have been associated with such illness, of which rhinovirus is the most common. Symptom production is a combination of viral cytopathic effect and the activation of inflammatory pathways. Therefore, antiviral treatment alone may not be able to prevent these events. The optimal use of such agents also requires earlier initiation; therefore, it is important to develop accurate and rapid diagnostic techniques for respiratory viruses. Before any reliable and effective treatment is available, symptomatic therapies may remain the only possible choice of management.

Identifiers

PMID15172021
PMCPMC7125703
OpenAlexW2024156216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.