ArticleMammalian genome : official journal of the International Mammalian Genome Society2004
Isolation from the horse genome of a new DNA transposon belonging to the Tigger family.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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Who cites it
2 citing papers in PubMed.
- Characterization of human gene locus CYYR1: a complex multi-transcript system.Molecular biology reports · 2014Article
- Investigation of the origin and spread of a Mammalian transposable element based on current sequence diversity.Journal of molecular evolution · 2011Article
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Authors and funding
5 authors.
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Abstract
Tigger elements are human DNA transposons homologous to the pogo element of Drosophila melanogaster. They contain an open reading frame for a transposase very similar to the major mammalian centromere protein CENP-B. We found in the horse genome a DNA element ( Ecatig3) sharing 88% homology with human Tigger3. The presence of Tigger elements in the horse genome confirms previous data that date these elements before the divergence between Perissodactyla and Primates (80-90 Myr ago). Copy number evaluation indicates that the horse element is much more abundant than its human counterpart. Southern blot analysis demonstrates that Ecatig3 elements are extremely homogeneous; this may indicate that the evolution of this DNA transposon has been driven by some kind of selection and has not been neutral.
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