ArticleMammalian genome : official journal of the International Mammalian Genome Society2004
Confirmation and dissection of QTL controlling resistance to malaria in mice.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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Who cites it
29 citing papers in PubMed.
- Genetic mapping of determinants in drug resistance, virulence, disease susceptibility, and interaction of host-rodent malaria parasites.Parasitology international · 2022Review
- Forward Genetics in Apicomplexa Biology: The Host Side of the Story.Frontiers in cellular and infection microbiology · 2022Review
- Mouse NC/Jic strain provides novel insights into host genetic factors for malaria research.Experimental animals · 2019Review
- Host genetics in malaria: lessons from mouse studies.Mammalian genome : official journal of the International Mammalian Genome Society · 2018Review
- Article
- The mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria.PloS one · 2017Article
- Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice.BMC genomics · 2016Article
- Susceptibility to Klebsiella pneumonaie infection in collaborative cross mice is a complex trait controlled by at least three loci acting at different time points.BMC genomics · 2014Article
- Fine-mapping QTLs in advanced intercross lines and other outbred populations.Mammalian genome : official journal of the International Mammalian Genome Society · 2014Review
- A genome scan for Plasmodium falciparum malaria identifies quantitative trait loci on chromosomes 5q31, 6p21.3, 17p12, and 19p13.Malaria journal · 2014Article
- Heritability and coefficient of genetic variation analyses of phenotypic traits provide strong basis for high-resolution QTL mapping in the Collaborative Cross mouse genetic reference population.Mammalian genome : official journal of the International Mammalian Genome Society · 2014Article
- Identification of the Plasmodium berghei resistance locus 9 linked to survival on chromosome 9.Malaria journal · 2013Article
- Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.Malaria journal · 2012Article
- Genetic control of susceptibility to infection with Plasmodium chabaudi chabaudi AS in inbred mouse strains.Genes and immunity · 2012Article
- Article
- Host resistance to malaria: using mouse models to explore the host response.Mammalian genome : official journal of the International Mammalian Genome Society · 2011Review
- Article
- Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-gamma as contributing to enhanced malaria survival.PloS one · 2010Article
- Loss of ability to self-heal malaria upon taurine transporter deletion.Infection and immunity · 2010Article
- RandoMate: a program for the generation of random mating schemes for small laboratory animals.Mammalian genome : official journal of the International Mammalian Genome Society · 2009Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility and resistance were genotyped for microsatellite markers on Chromosomes (Chrs) 5, 8, and 17. QTL originally detected in backcross and F(2) populations were confirmed on the three chromosomes within narrower genomic regions, by maximum likelihood and regression analyses. Each of the previously mapped QTL on Chrs 5 and 17 resolved into two linked QTLs. The distal and proximal QTLs on Chrs 5 and 17, respectively, map to the previously reported QTL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.