Evidence map›Paper›PMID 15166153›Full record

ArticleGenetics2004

Mutational analysis of the Drosophila DNA repair and recombination gene mei-9.

Ozlem Yildiz, Hutton Kearney, Benjamin C Kramer, Jeff J Sekelsky

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ozlem YildizDepartment of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
Hutton Kearney
Benjamin C Kramer
Jeff J Sekelsky
University of North Carolina at Chapel Hill · US

Funding

Meiotic Recombination in DrosophilaR01GM061252 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SEKELSKY, JEFF J. · 2000 to 2015
$4.1M
NIGMS NIH HHS GM61252NIGMS NIH HHS R01 GM061252
6 · The paper itself

Abstract

Drosophila mei-9 is essential for several DNA repair and recombination pathways, including nucleotide excision repair (NER), interstrand crosslink repair, and meiotic recombination. To better understand the role of MEI-9 in these processes, we characterized 10 unique mutant alleles of mei-9. These include a P-element insertion that disrupts repair functions but not the meiotic function; three nonsense mutations, one of which has nearly wild-type levels of protein; three missense mutations, one of which disrupts the meiotic function but not repair functions; two small in-frame deletions; and one frameshift.

Indexed as

DNA Mutational AnalysisDNA RepairRecombination, GeneticAllelesAmino Acid MotifsAmino Acid SequenceAnimalsBlotting, WesternCodon, NonsenseDNA DamageDrosophila melanogasterDrosophila ProteinsFrameshift MutationGene DeletionMeiosisModels, GeneticCodon, NonsenseDrosophila ProteinsMEI-9 protein, DrosophilaNuclear Proteins

Identifiers

PMID15166153
PMCPMC1470841
OpenAlexW2166686674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.