ArticleImmunogenetics2004
Detection of 14 alleles derived from the MHC class I A locus in cynomolgus monkeys.
Article in Immunogenetics, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Review
- Major histocompatibility complex haplotyping and long-amplicon allele discovery in cynomolgus macaques from Chinese breeding facilities.Immunogenetics · 2017Article
- Discovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencing: Mafa-class I polymorphism.Immunogenetics · 2015Article
- Multilocus definition of MHC haplotypes in pedigreed cynomolgus macaques (Macaca fascicularis).Immunogenetics · 2012Article
- Diversity of MHC class I haplotypes in cynomolgus macaques.Immunogenetics · 2012Article
- Study of cynomolgus monkey (Macaca fascicularis) DRA polymorphism in four populations.Immunogenetics · 2010Article
- MHC class I A loci polymorphism and diversity in three Southeast Asian populations of cynomolgus macaque.Immunogenetics · 2009Article
- Mauritian cynomolgus macaques share two exceptionally common major histocompatibility complex class I alleles that restrict simian immunodeficiency virus-specific CD8+ T cells.Journal of virology · 2009Article
- Characterization of 47 MHC class I sequences in Filipino cynomolgus macaques.Immunogenetics · 2009Article
- MHC haplotype frequencies in a UK breeding colony of Mauritian cynomolgus macaques mirror those found in a distinct population from the same geographic origin.Journal of medical primatology · 2009Article
- MHC class I characterization of Indonesian cynomolgus macaques.Immunogenetics · 2008Article
- Allelic diversity within the high frequency Mamu-A2*05/Mane-A2*05 (Mane-A*06)/Mafa-A2*05 family of macaque MHC-A loci.Tissue antigens · 2008Article
- MHC class I A region diversity and polymorphism in macaque species.Immunogenetics · 2007Article
- The locus encoding an oligomorphic family of MHC-A alleles (Mane-A*06/Mamu-A*05) is present at high frequency in several macaque species.Immunogenetics · 2007Article
- Simian immunodeficiency virus SIVmac239 infection of major histocompatibility complex-identical cynomolgus macaques from Mauritius.Journal of virology · 2007Article
- Extensive sharing of MHC class II alleles between rhesus and cynomolgus macaques.Immunogenetics · 2006Article
- Identification of the MHC class I B locus in cynomolgus monkeys.Immunogenetics · 2005Article
- Unparalleled complexity of the MHC class I region in rhesus macaques.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A basic understanding of the major histocompatibility complex (MHC) class I, which, together with T-cell receptors, is a key player in antigen recognition by cytotoxic T lymphocytes, is necessary to study the cellular immune response to intracellular pathogens. The MHC has hardly been reported in cynomolgus monkeys ( Macaca facicularis), although cynomolgus monkeys have been frequently used as the surrogate animal model. We attempted to determine the nucleotide sequences of the MHC class I A locus of cynomolgus monkeys ( Mafa-A) and eventually 34 independent sequences of Mafa-A were obtained from 29 cynomolgus monkeys. These 34 sequences were classified into 14 Mafa-A alleles according to the results of phylogenetic analyses using the neighbor-joining method. One to three Mafa-A alleles were obtained from a single animal. We also tried to establish a multiplex PCR-SSP method for convenient typing of Mafa-A alleles. cDNA from a family of cynomolgus monkeys, which is composed of four sirs and four dams, were examined by multiplex PCR-SSP. The result of multiplex PCR-SSP showed that an individual cynomolgus monkey had two or three Mafa-A alleles, suggesting that the A locus of cynomolgus monkeys might be duplicated.
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